MET Receptor Tyrosine Kinase Inhibition Reduces Interferon-Gamma (IFN-γ)-Stimulated PD-L1 Expression through the STAT3 Pathway in Melanoma Cells

SIMPLE SUMMARY: While the treatment of melanoma was revolutionized about a decade ago by the introduction of immunotherapies and targeted therapies, advanced melanoma remains a therapeutic challenge. Here we demonstrate a cross-talk between a checkpoint protein, PD-L1, and a receptor tyrosine kinase...

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Detalles Bibliográficos
Autores principales: Song, Kyu Young, Han, Yong Hwan, Roehrich, Heidi, Brown, Mary E., Torres-Cabala, Carlos, Giubellino, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340457/
https://www.ncbi.nlm.nih.gov/pubmed/37444518
http://dx.doi.org/10.3390/cancers15133408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340457/
https://www.ncbi.nlm.nih.gov/pubmed/37444518
http://dx.doi.org/10.3390/cancers15133408

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