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MET Receptor Tyrosine Kinase Inhibition Reduces Interferon-Gamma (IFN-γ)-Stimulated PD-L1 Expression through the STAT3 Pathway in Melanoma Cells
SIMPLE SUMMARY: While the treatment of melanoma was revolutionized about a decade ago by the introduction of immunotherapies and targeted therapies, advanced melanoma remains a therapeutic challenge. Here we demonstrate a cross-talk between a checkpoint protein, PD-L1, and a receptor tyrosine kinase...
Autores principales: | Song, Kyu Young, Han, Yong Hwan, Roehrich, Heidi, Brown, Mary E., Torres-Cabala, Carlos, Giubellino, Alessio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340457/ https://www.ncbi.nlm.nih.gov/pubmed/37444518 http://dx.doi.org/10.3390/cancers15133408 |
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