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Identification of a Novel SSTR3 Full Agonist for the Treatment of Nonfunctioning Pituitary Adenomas

SIMPLE SUMMARY: Therapy for nonfunctioning pituitary adenomas (NFPAs) is a significant unmet medical need since these adenomas are frequently invasive, are difficult to resect completely and often recur. NFPAs express high levels of somatostatin receptor 3 (SSTR3), and SSTR3 agonists could be a prom...

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Detalles Bibliográficos
Autores principales: Modena, Daniela, Moras, Maria Luisa, Sandrone, Giovanni, Stevenazzi, Andrea, Vergani, Barbara, Dasgupta, Pooja, Kliever, Andrea, Gulde, Sebastian, Marangelo, Alessandro, Schillmaier, Mathias, Luque, Raul M., Bäuerle, Stephen, Pellegata, Natalia S., Schulz, Stefan, Steinkühler, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340464/
https://www.ncbi.nlm.nih.gov/pubmed/37444563
http://dx.doi.org/10.3390/cancers15133453