Methylglyoxal Impairs the Pro-Angiogenic Ability of Mouse Adipose-Derived Stem Cells (mADSCs) via a Senescence-Associated Mechanism

Adipose-derived stem cells (ADSCs) play a crucial role in angiogenesis and repair of damaged tissues. However, in pathological conditions including diabetes, ADSC function is compromised. This work aims at evaluating the effect of Methylglyoxal (MGO), a product of chronic hyperglycemia, on mouse ADS...

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Detalles Bibliográficos
Autores principales: Leone, Alessia, Nicolò, Antonella, Prevenzano, Immacolata, Zatterale, Federica, Longo, Michele, Desiderio, Antonella, Spinelli, Rosa, Campitelli, Michele, Conza, Domenico, Raciti, Gregory Alexander, Beguinot, Francesco, Nigro, Cecilia, Miele, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340470/
https://www.ncbi.nlm.nih.gov/pubmed/37443775
http://dx.doi.org/10.3390/cells12131741

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