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ExtRanFS: An Automated Lung Cancer Malignancy Detection System Using Extremely Randomized Feature Selector

Lung cancer is an abnormality where the body’s cells multiply uncontrollably. The disease can be deadly if not detected in the initial stage. To address this issue, an automated lung cancer malignancy detection (ExtRanFS) framework is developed using transfer learning. We used the IQ-OTH/NCCD datase...

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Autores principales: V. R., Nitha, Chandra S. S., Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340584/
https://www.ncbi.nlm.nih.gov/pubmed/37443600
http://dx.doi.org/10.3390/diagnostics13132206
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author V. R., Nitha
Chandra S. S., Vinod
author_facet V. R., Nitha
Chandra S. S., Vinod
author_sort V. R., Nitha
collection PubMed
description Lung cancer is an abnormality where the body’s cells multiply uncontrollably. The disease can be deadly if not detected in the initial stage. To address this issue, an automated lung cancer malignancy detection (ExtRanFS) framework is developed using transfer learning. We used the IQ-OTH/NCCD dataset gathered from the Iraq Hospital in 2019, encompassing CT scans of patients suffering from various lung cancers and healthy subjects. The annotated dataset consists of CT slices from 110 patients, of which 40 were diagnosed with malignant tumors and 15 with benign tumors. Fifty-five patients were determined to be in good health. All CT images are in DICOM format with a 1mm slice thickness, consisting of 80 to 200 slices at various sides and angles. The proposed system utilized a convolution-based pre-trained VGG16 model as the feature extractor and an Extremely Randomized Tree Classifier as the feature selector. The selected features are fed to the Multi-Layer Perceptron (MLP) Classifier for detecting whether the lung cancer is benign, malignant, or normal. The accuracy, sensitivity, and F1-Score of the proposed framework are 99.09%, 98.33%, and 98.33%, respectively. To evaluate the proposed model, a comparison is performed with other pre-trained models as feature extractors and also with the existing state-of-the-art methodologies as classifiers. From the experimental results, it is evident that the proposed framework outperformed other existing methodologies. This work would be beneficial to both the practitioners and the patients in identifying whether the tumor is benign, malignant, or normal.
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spelling pubmed-103405842023-07-14 ExtRanFS: An Automated Lung Cancer Malignancy Detection System Using Extremely Randomized Feature Selector V. R., Nitha Chandra S. S., Vinod Diagnostics (Basel) Article Lung cancer is an abnormality where the body’s cells multiply uncontrollably. The disease can be deadly if not detected in the initial stage. To address this issue, an automated lung cancer malignancy detection (ExtRanFS) framework is developed using transfer learning. We used the IQ-OTH/NCCD dataset gathered from the Iraq Hospital in 2019, encompassing CT scans of patients suffering from various lung cancers and healthy subjects. The annotated dataset consists of CT slices from 110 patients, of which 40 were diagnosed with malignant tumors and 15 with benign tumors. Fifty-five patients were determined to be in good health. All CT images are in DICOM format with a 1mm slice thickness, consisting of 80 to 200 slices at various sides and angles. The proposed system utilized a convolution-based pre-trained VGG16 model as the feature extractor and an Extremely Randomized Tree Classifier as the feature selector. The selected features are fed to the Multi-Layer Perceptron (MLP) Classifier for detecting whether the lung cancer is benign, malignant, or normal. The accuracy, sensitivity, and F1-Score of the proposed framework are 99.09%, 98.33%, and 98.33%, respectively. To evaluate the proposed model, a comparison is performed with other pre-trained models as feature extractors and also with the existing state-of-the-art methodologies as classifiers. From the experimental results, it is evident that the proposed framework outperformed other existing methodologies. This work would be beneficial to both the practitioners and the patients in identifying whether the tumor is benign, malignant, or normal. MDPI 2023-06-29 /pmc/articles/PMC10340584/ /pubmed/37443600 http://dx.doi.org/10.3390/diagnostics13132206 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
V. R., Nitha
Chandra S. S., Vinod
ExtRanFS: An Automated Lung Cancer Malignancy Detection System Using Extremely Randomized Feature Selector
title ExtRanFS: An Automated Lung Cancer Malignancy Detection System Using Extremely Randomized Feature Selector
title_full ExtRanFS: An Automated Lung Cancer Malignancy Detection System Using Extremely Randomized Feature Selector
title_fullStr ExtRanFS: An Automated Lung Cancer Malignancy Detection System Using Extremely Randomized Feature Selector
title_full_unstemmed ExtRanFS: An Automated Lung Cancer Malignancy Detection System Using Extremely Randomized Feature Selector
title_short ExtRanFS: An Automated Lung Cancer Malignancy Detection System Using Extremely Randomized Feature Selector
title_sort extranfs: an automated lung cancer malignancy detection system using extremely randomized feature selector
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340584/
https://www.ncbi.nlm.nih.gov/pubmed/37443600
http://dx.doi.org/10.3390/diagnostics13132206
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