Cargando…

Inhibition of Monoacylglycerol Lipase Decreases Angiogenic Features of Endothelial Cells via Release of Tissue Inhibitor of Metalloproteinase-1 from Lung Cancer Cells

Despite the well-described anticarcinogenic effects of endocannabinoids, the influence of the endocannabinoid system on tumor angiogenesis is still debated. In the present study, conditioned medium (CM) from A549 and H358 lung cancer cells treated with ascending concentrations of the monoacylglycero...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wittig, Felix, Henkel, Lino, Prüser, Jan Lukas, Merkord, Jutta, Ramer, Robert, Hinz, Burkhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340590/ https://www.ncbi.nlm.nih.gov/pubmed/37443791 http://dx.doi.org/10.3390/cells12131757

Ejemplares similares

Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells
por: Winkler, Katrin, et al.
Publicado: (2016)

The antiangiogenic action of cisplatin on endothelial cells is mediated through the release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells
por: Ramer, Robert, et al.
Publicado: (2018)

Monoacylglycerol Lipase Regulates Fever Response
por: Sanchez-Alavez, Manuel, et al.
Publicado: (2015)

Monoacylglycerol Lipase Knockdown Inhibits Cell Proliferation and Metastasis in Lung Adenocarcinoma
por: Zhang, Hao, et al.
Publicado: (2020)

Conformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol Lipase
por: Rengachari, Srinivasan, et al.
Publicado: (2013)

Conformational gating, dynamics and allostery in human monoacylglycerol lipase
por: Tyukhtenko, Sergiy, et al.
Publicado: (2020)

Effect of monoacylglycerol lipase on the tumor growth in endometrial cancer
por: Li, Xin, et al.
Publicado: (2019)

Localization of diacylglycerol lipase alpha and monoacylglycerol lipase during postnatal development of the rat retina
por: Cécyre, Bruno, et al.
Publicado: (2014)

N-terminal domain replacement changes an archaeal monoacylglycerol lipase into a triacylglycerol lipase
por: Soni, Surabhi, et al.
Publicado: (2019)

Monoacylglycerol lipase reprograms lipid precursors signaling in liver disease
por: Tardelli, Matteo
Publicado: (2020)

Targeting Monoacylglycerol Lipase in Pursuit of Therapies for Neurological and Neurodegenerative Diseases
por: Zanfirescu, Anca, et al.
Publicado: (2021)

Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration
por: Allaire, Manon, et al.
Publicado: (2023)

Antiangiogenic Action of JZL184 on Endothelial Cells via Inhibition of VEGF Expression in Hypoxic Lung Cancer Cells
por: Wittig, Felix, et al.
Publicado: (2023)

Interleukin-1β Induces Tissue Factor Expression in A549 Cells via EGFR-Dependent and -Independent Mechanisms
por: Mechelke, Tobias, et al.
Publicado: (2021)

Inhibition of Monoacylglycerol Lipase Activity Decreases Glucose-Stimulated Insulin Secretion in INS-1 (832/13) Cells and Rat Islets
por: Berdan, Charles A., et al.
Publicado: (2016)

The Endocannabinoid System as a Pharmacological Target for New Cancer Therapies
por: Ramer, Robert, et al.
Publicado: (2021)

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
por: Schlosburg, Joel E., et al.
Publicado: (2010)

Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice
por: Costola-de-Souza, Carolina, et al.
Publicado: (2013)

Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase
por: Tyukhtenko, Sergiy, et al.
Publicado: (2018)

A New Ultrasensitive Bioluminescence-Based Method for Assaying Monoacylglycerol Lipase
por: Miceli, Matteo, et al.
Publicado: (2021)

Endocannabinoid control of neuroinflammation in traumatic brain injury by monoacylglycerol lipase in astrocytes
por: Chen, Chu
Publicado: (2022)

Nausea-Induced 5-HT Release in the Interoceptive Insular Cortex and Regulation by Monoacylglycerol Lipase (MAGL) Inhibition and Cannabidiol
por: Limebeer, Cheryl L., et al.
Publicado: (2018)

Neuronal and Astrocytic Monoacylglycerol Lipase Limit the Spread of Endocannabinoid Signaling in the Cerebellum123
por: Chen, Yao, et al.
Publicado: (2016)

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism
por: Heier, Christoph, et al.
Publicado: (2016)

Effect of Monoacylglycerol Lipase Inhibition on Intestinal Permeability of Rats With Severe Acute Pancreatitis
por: Wang, Jing, et al.
Publicado: (2022)

Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives
por: Bononi, Giulia, et al.
Publicado: (2022)

Monoacylglycerol lipase deficiency in the tumor microenvironment slows tumor growth in non-small cell lung cancer
por: Kienzl, Melanie, et al.
Publicado: (2021)

Study on a Novel Cold-Active and Halotolerant Monoacylglycerol Lipase Widespread in Marine Bacteria Reveals a New Group of Bacterial Monoacylglycerol Lipases Containing Unusual C(A/S)HSMG Catalytic Motifs
por: Li, Ping-Yi, et al.
Publicado: (2020)

Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex
por: Pavón, Francisco Javier, et al.
Publicado: (2021)

Modulation of mRNA Expression of Monoacylglycerol Lipase, Diacylglycerol Lipase and Cannabinoid Receptor-1 in Mice Experimentally Infected with T. gondii
por: Rostami-Mansoor, Sahar, et al.
Publicado: (2021)

Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase: New Targets for Future Antidepressants
por: Ogawa, Shintaro, et al.
Publicado: (2015)

Robust anti‐nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain
por: Burston, James J, et al.
Publicado: (2016)

Monoacylglycerol Lipase: A Novel Potential Therapeutic Target and Prognostic Indicator for Hepatocellular Carcinoma
por: Zhang, Junyong, et al.
Publicado: (2016)

Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression
por: Xiang, Wei, et al.
Publicado: (2018)

The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition
por: Aschauer, Philipp, et al.
Publicado: (2018)

Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis
por: Tardelli, Matteo, et al.
Publicado: (2019)

Monoacylglycerol lipase inhibitors: modulators for lipid metabolism in cancer malignancy, neurological and metabolic disorders
por: Deng, Hui, et al.
Publicado: (2020)

Analgesic and Anticancer Activity of Benzoxazole Clubbed 2-Pyrrolidinones as Novel Inhibitors of Monoacylglycerol Lipase
por: Afzal, Obaid, et al.
Publicado: (2021)

Corrigendum: Effect of Monoacylglycerol Lipase Inhibition on Intestinal Permeability of Rats With Severe Acute Pancreatitis
por: Wang, Jing, et al.
Publicado: (2022)

Monoacylglycerol lipase regulates macrophage polarization and cancer progression in uveal melanoma and pan-cancer
por: Tan, Yao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rr0q37dae48vtmuapcoemr6b92