LRRK2 Kinase Inhibition Attenuates Neuroinflammation and Cytotoxicity in Animal Models of Alzheimer’s and Parkinson’s Disease-Related Neuroinflammation

Chronic neuroinflammation plays a crucial role in the progression of several neurodegenerative diseases (NDDs), including Parkinson’s disease (PD) and Alzheimer’s disease (AD). Intriguingly, in the last decade, leucine-rich repeat kinase-2 (LRRK2), a gene mutated in familial and sporadic PD, was rev...

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Detalles Bibliográficos
Autores principales: Mutti, Veronica, Carini, Giulia, Filippini, Alice, Castrezzati, Stefania, Giugno, Lorena, Gennarelli, Massimo, Russo, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340668/
https://www.ncbi.nlm.nih.gov/pubmed/37443833
http://dx.doi.org/10.3390/cells12131799

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