Astragaloside IV Blunts Epithelial–Mesenchymal Transition and G2/M Arrest to Alleviate Renal Fibrosis via Regulating ALDH2-Mediated Autophagy

Previous studies show that astragaloside IV (ASIV) has anti-renal fibrosis effects. However, its mechanism remains elusive. In this study, we investigated the anti-fibrosis mechanisms of ASIV on chronic kidney disease (CKD) in vivo and in vitro. A CKD model was induced in rats with adenine (200 mg/k...

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Detalles Bibliográficos
Autores principales: Li, Dong, Liu, Yuzhe, Zhan, Quancao, Zeng, Yan, Peng, Ze, He, Qifeng, Tan, Qi, Cao, Wenfu, Wang, Shang, Wang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340704/
https://www.ncbi.nlm.nih.gov/pubmed/37443810
http://dx.doi.org/10.3390/cells12131777

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