Cargando…

Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase

Inhibitors of gamma-glutamyl transpeptidase (GGT1, aka gamma-glutamyl transferase) are needed for the treatment of cancer, cardiovascular illness and other diseases. Compounds that inhibit GGT1 have been evaluated in the clinic, but no inhibitor has successfully demonstrated specific and systemic GG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Luong, Schultz, Daniel C., Terzyan, Simon S., Rezaei, Mohammad, Songb, Jinhua, Li, Chenglong, You, Youngjae, Hanigan, Marie H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340724/ https://www.ncbi.nlm.nih.gov/pubmed/36208545 http://dx.doi.org/10.1016/j.bmc.2022.116986

Ejemplares similares

Gamma-glutamyl transpeptidase to platelet and gamma-glutamyl transpeptidase to lymphocyte ratio in a sample of Chinese Han population
por: Chen, Weijie, et al.
Publicado: (2022)

An Electrochemical Method to Detect Gamma Glutamyl Transpeptidase
por: Chen, Guifang, et al.
Publicado: (2012)

The clinical implication of gamma-glutamyl transpeptidase in COVID-19()
por: Liu, Jianrong, et al.
Publicado: (2021)

Is gamma-glutamyl transpeptidase a biomarker for oxidative stress in periodontitis?
por: Sreeram, Meenakshi, et al.
Publicado: (2015)

Human germ cell tumours: expression of γ-glutamyl transpeptidase and sensitivity to cisplatin
por: Hanigan, M H, et al.
Publicado: (1999)

Drinking Amount Associated with Abnormal Gamma-Glutamyl Transpeptidase Expression in Women
por: Yang, Jun-Seok, et al.
Publicado: (2016)

Gamma-glutamyl transpeptidase in putative precancerous thyroid lesions of rats treated with diisopropanolnitrosamine.
por: Moriyama, S., et al.
Publicado: (1983)

Combination of Carcinoembryonic Antigen and Gamma Glutamyl Transpeptidase in the Study of The Evolution of Colorectal Cancer
por: Steele, L., et al.
Publicado: (1974)

Probing the Interactions of Sulfur-Containing Histidine Compounds with Human Gamma-Glutamyl Transpeptidase
por: Milito, Alfonsina, et al.
Publicado: (2019)

Serum levels of gamma-glutamyl transpeptidase in relation to HCC human biology and prognosis
por: Carr, BI, et al.
Publicado: (2020)

Diagnostic value of gamma‐glutamyl transpeptidase to alkaline phosphatase ratio combined with gamma‐glutamyl transpeptidase to aspartate aminotransferase ratio and alanine aminotransferase to aspartate aminotransferase ratio in alpha‐fetoprotein‐negative hepatocellular carcinoma
por: Li, Jiang, et al.
Publicado: (2021)

Role of Campylobacter jejuni gamma-glutamyl transpeptidase on epithelial cell apoptosis and lymphocyte proliferation
por: Floch, Pauline, et al.
Publicado: (2014)

“Phylogenetic and evolutionary analysis of functional divergence among Gamma glutamyl transpeptidase (GGT) subfamilies”
por: Verma, Ved Vrat, et al.
Publicado: (2015)

High pretreatment serum gamma-glutamyl transpeptidase predicts an inferior outcome in nasopharyngeal carcinoma
por: Luo, Min, et al.
Publicado: (2017)

Expression Status and Prognostic Significance of Gamma-Glutamyl Transpeptidase Family Genes in Hepatocellular Carcinoma
por: Tian, Shan, et al.
Publicado: (2021)

Gut microbiome is associated with metabolic syndrome accompanied by elevated gamma-glutamyl transpeptidase in men
por: Sheng, Shifeng, et al.
Publicado: (2022)

Early elevated serum gamma glutamyl transpeptidase after liver transplantation is associated with better survival
por: Alkozai, Edris M, et al.
Publicado: (2014)

The value of neutrophil to lymphocyte ratio and gamma-glutamyl transpeptidase to platelet ratio in patients with hepatocellular carcinoma
por: Hu, Zuojian, et al.
Publicado: (2019)

Prognostic significance of gamma‐glutamyl transpeptidase to albumin ratio in patients with intrahepatic cholangiocarcinoma after hepatectomy
por: Li, Hui, et al.
Publicado: (2022)

Elevated gamma-glutamyl transpeptidase level is associated with an increased risk of hip fracture in postmenopausal women
por: Kim, Kyoung Jin, et al.
Publicado: (2022)

Tumor and serum gamma-glutamyl transpeptidase, new prognostic and molecular interpretation of an old biomarker in gastric cancer
por: Wang, Qinchuan, et al.
Publicado: (2017)

Predictive value of gamma-glutamyl transpeptidase to lymphocyte count ratio in hepatocellular carcinoma patients with microvascular invasion
por: Zhang, Hongxing, et al.
Publicado: (2020)

Bacterial Gamma-Glutamyl Transpeptidase, an Emerging Biocatalyst: Insights Into Structure–Function Relationship and Its Biotechnological Applications
por: Saini, Meenu, et al.
Publicado: (2021)

Evaluation of salivary gamma-glutamyl transpeptidase as a biomarker in oral squamous cell carcinoma and precancerous lesions
por: Mujawar, Salim Javeed, et al.
Publicado: (2020)

Circulating gamma‐glutamyl transpeptidase and risk of pancreatic cancer: A prospective cohort study in the UK Biobank
por: Liao, Weiting, et al.
Publicado: (2022)

Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site
por: Terzyan, Simon S., et al.
Publicado: (2020)

Simple models based on gamma-glutamyl transpeptidase and platelets for predicting survival in hepatitis B-associated hepatocellular carcinoma
por: Pang, Qing, et al.
Publicado: (2016)

Rapid detection of metastatic lymph nodes of colorectal cancer with a gamma-glutamyl transpeptidase-activatable fluorescence probe
por: Kubo, Hidemasa, et al.
Publicado: (2018)

Gamma-Glutamyl Transpeptidase-to-Platelet Ratio Predicts Significant Liver Fibrosis of Chronic Hepatitis B Patients in China
por: Ren, Tianyi, et al.
Publicado: (2017)

Atorvastatin associated with gamma glutamyl transpeptidase elevation in a hyperlipidemia patient: A case report and literature review
por: Xu, Yan, et al.
Publicado: (2020)

Gamma-Glutamyl Transpeptidase to Platelet Ratio: A New Inflammatory Marker Associated with Outcomes after Cardiac Arrest
por: Zhao, Yipin, et al.
Publicado: (2021)

Low gamma-glutamyl transpeptidase levels at presentation are associated with severity of liver illness and poor outcome in biliary atresia
por: Sun, Song, et al.
Publicado: (2022)

Serum Gamma-Glutamyl Transpeptidase-to-Platelet Ratio as a Noninvasive Marker of Liver Fibrosis in Chronic Hepatitis B
por: Purkayastha, Subham, et al.
Publicado: (2023)

Detection of distinct glycosylation patterns on human γ-glutamyl transpeptidase 1 using antibody-lectin sandwich array (ALSA) technology
por: West, Matthew B, et al.
Publicado: (2014)

Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
por: Pereira, M A, et al.
Publicado: (1983)

Garlic γ-glutamyl transpeptidases that catalyze deglutamylation of biosynthetic intermediate of alliin
por: Yoshimoto, Naoko, et al.
Publicado: (2015)

γ-Glutamyl-Transpeptidase-Resistant Glutathione Analog Attenuates Progression of Alzheimer’s Disease-like Pathology and Neurodegeneration in a Mouse Model
por: Christopher Kwon, Ye In, et al.
Publicado: (2021)

Diagnostic value of fibrinogen to prealbumin ratio and gamma-glutamyl transpeptidase to platelet ratio in the progression of AFP-negative hepatocellular carcinoma
por: Huang, Li, et al.
Publicado: (2020)

Increased Uric Acid, Gamma-Glutamyl Transpeptidase and Alkaline Phosphatase in Early-Pregnancy Associated With the Development of Gestational Hypertension and Preeclampsia
por: Chen, Yequn, et al.
Publicado: (2021)

Novel Nomograms Based on Gamma-Glutamyl Transpeptidase-to-Lymphocyte Ratio Predict Prognosis of Hepatocellular Carcinoma Patients After Hepatectomy
por: Ma, Cheng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_i2va3bc012begi5o2b2nvmne5s