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Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase

Inhibitors of gamma-glutamyl transpeptidase (GGT1, aka gamma-glutamyl transferase) are needed for the treatment of cancer, cardiovascular illness and other diseases. Compounds that inhibit GGT1 have been evaluated in the clinic, but no inhibitor has successfully demonstrated specific and systemic GG...

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Detalles Bibliográficos
Autores principales:	Nguyen, Luong, Schultz, Daniel C., Terzyan, Simon S., Rezaei, Mohammad, Songb, Jinhua, Li, Chenglong, You, Youngjae, Hanigan, Marie H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340724/ https://www.ncbi.nlm.nih.gov/pubmed/36208545 http://dx.doi.org/10.1016/j.bmc.2022.116986

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