Dissecting the Methylomes of EGFR-Amplified Glioblastoma Reveals Altered DNA Replication and Packaging, and Chromatin and Gene Silencing Pathways

SIMPLE SUMMARY: Glioblastoma is the most malignant brain tumor. To date, there is no curative therapy available. Since EGFR is an interesting candidate in precision medicine, we performed an integrated molecular analysis in glioblastoma with and without EGFR amplification. We found that there are si...

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Detalles Bibliográficos
Autores principales: Kraus, Theo F. J., Langwieder, Celina K., Hölzl, Dorothee, Hutarew, Georg, Schlicker, Hans U., Alinger-Scharinger, Beate, Schwartz, Christoph, Sotlar, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341082/
https://www.ncbi.nlm.nih.gov/pubmed/37444635
http://dx.doi.org/10.3390/cancers15133525

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