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Ultra-High-Resolution Photon-Counting Detector CT Arthrography of the Ankle: A Feasibility Study
This study was designed to investigate the image quality of ultra-high-resolution ankle arthrography employing a photon-counting detector CT. Bilateral arthrograms were acquired in four cadaveric specimens with full-dose (10 mGy) and low-dose (3 mGy) scan protocols. Three convolution kernels with di...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341106/ https://www.ncbi.nlm.nih.gov/pubmed/37443595 http://dx.doi.org/10.3390/diagnostics13132201 |
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author | Luetkens, Karsten Sebastian Grunz, Jan-Peter Kunz, Andreas Steven Huflage, Henner Weißenberger, Manuel Hartung, Viktor Patzer, Theresa Sophie Gruschwitz, Philipp Ergün, Süleyman Bley, Thorsten Alexander Feldle, Philipp |
author_facet | Luetkens, Karsten Sebastian Grunz, Jan-Peter Kunz, Andreas Steven Huflage, Henner Weißenberger, Manuel Hartung, Viktor Patzer, Theresa Sophie Gruschwitz, Philipp Ergün, Süleyman Bley, Thorsten Alexander Feldle, Philipp |
author_sort | Luetkens, Karsten Sebastian |
collection | PubMed |
description | This study was designed to investigate the image quality of ultra-high-resolution ankle arthrography employing a photon-counting detector CT. Bilateral arthrograms were acquired in four cadaveric specimens with full-dose (10 mGy) and low-dose (3 mGy) scan protocols. Three convolution kernels with different spatial frequencies were utilized for image reconstruction (ρ(50); Br98: 39.0, Br84: 22.6, Br76: 16.5 lp/cm). Seven radiologists subjectively assessed the image quality regarding the depiction of bone, hyaline cartilage, and ligaments. An additional quantitative assessment comprised the measurement of noise and the computation of contrast-to-noise ratios (CNR). While an optimal depiction of bone tissue was achieved with the ultra-sharp Br98 kernel (S ≤ 0.043), the visualization of cartilage improved with lower modulation transfer functions at each dose level (p ≤ 0.014). The interrater reliability ranged from good to excellent for all assessed tissues (intraclass correlation coefficient ≥ 0.805). The noise levels in subcutaneous fat decreased with reduced spatial frequency (p < 0.001). Notably, the low-dose Br76 matched the CNR of the full-dose Br84 (p > 0.999) and superseded Br98 (p < 0.001) in all tissues. Based on the reported results, a photon-counting detector CT arthrography of the ankle with an ultra-high-resolution collimation offers stellar image quality and tissue assessability, improving the evaluation of miniscule anatomical structures. While bone depiction was superior in combination with an ultra-sharp convolution kernel, soft tissue evaluation benefited from employing a lower spatial frequency. |
format | Online Article Text |
id | pubmed-10341106 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103411062023-07-14 Ultra-High-Resolution Photon-Counting Detector CT Arthrography of the Ankle: A Feasibility Study Luetkens, Karsten Sebastian Grunz, Jan-Peter Kunz, Andreas Steven Huflage, Henner Weißenberger, Manuel Hartung, Viktor Patzer, Theresa Sophie Gruschwitz, Philipp Ergün, Süleyman Bley, Thorsten Alexander Feldle, Philipp Diagnostics (Basel) Article This study was designed to investigate the image quality of ultra-high-resolution ankle arthrography employing a photon-counting detector CT. Bilateral arthrograms were acquired in four cadaveric specimens with full-dose (10 mGy) and low-dose (3 mGy) scan protocols. Three convolution kernels with different spatial frequencies were utilized for image reconstruction (ρ(50); Br98: 39.0, Br84: 22.6, Br76: 16.5 lp/cm). Seven radiologists subjectively assessed the image quality regarding the depiction of bone, hyaline cartilage, and ligaments. An additional quantitative assessment comprised the measurement of noise and the computation of contrast-to-noise ratios (CNR). While an optimal depiction of bone tissue was achieved with the ultra-sharp Br98 kernel (S ≤ 0.043), the visualization of cartilage improved with lower modulation transfer functions at each dose level (p ≤ 0.014). The interrater reliability ranged from good to excellent for all assessed tissues (intraclass correlation coefficient ≥ 0.805). The noise levels in subcutaneous fat decreased with reduced spatial frequency (p < 0.001). Notably, the low-dose Br76 matched the CNR of the full-dose Br84 (p > 0.999) and superseded Br98 (p < 0.001) in all tissues. Based on the reported results, a photon-counting detector CT arthrography of the ankle with an ultra-high-resolution collimation offers stellar image quality and tissue assessability, improving the evaluation of miniscule anatomical structures. While bone depiction was superior in combination with an ultra-sharp convolution kernel, soft tissue evaluation benefited from employing a lower spatial frequency. MDPI 2023-06-28 /pmc/articles/PMC10341106/ /pubmed/37443595 http://dx.doi.org/10.3390/diagnostics13132201 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Luetkens, Karsten Sebastian Grunz, Jan-Peter Kunz, Andreas Steven Huflage, Henner Weißenberger, Manuel Hartung, Viktor Patzer, Theresa Sophie Gruschwitz, Philipp Ergün, Süleyman Bley, Thorsten Alexander Feldle, Philipp Ultra-High-Resolution Photon-Counting Detector CT Arthrography of the Ankle: A Feasibility Study |
title | Ultra-High-Resolution Photon-Counting Detector CT Arthrography of the Ankle: A Feasibility Study |
title_full | Ultra-High-Resolution Photon-Counting Detector CT Arthrography of the Ankle: A Feasibility Study |
title_fullStr | Ultra-High-Resolution Photon-Counting Detector CT Arthrography of the Ankle: A Feasibility Study |
title_full_unstemmed | Ultra-High-Resolution Photon-Counting Detector CT Arthrography of the Ankle: A Feasibility Study |
title_short | Ultra-High-Resolution Photon-Counting Detector CT Arthrography of the Ankle: A Feasibility Study |
title_sort | ultra-high-resolution photon-counting detector ct arthrography of the ankle: a feasibility study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341106/ https://www.ncbi.nlm.nih.gov/pubmed/37443595 http://dx.doi.org/10.3390/diagnostics13132201 |
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