Radiation-Induced Cellular Senescence Reduces Susceptibility of Glioblastoma Cells to Oncolytic Vaccinia Virus

SIMPLE SUMMARY: Novel therapeutic approaches combining oncolytic virus (OV) therapy and radiotherapy are being investigated to improve treatment for glioblastoma (GBM). However, following radiotherapy cellular senescence is induced in a portion of GBM cells and it is unknown how the radiation-induce...

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Detalles Bibliográficos
Autores principales: Storozynsky, Quinn T., Han, Xuefei, Komant, Shae, Agopsowicz, Kate C., Potts, Kyle G., Gamper, Armin M., Godbout, Roseline, Evans, David H., Hitt, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341205/
https://www.ncbi.nlm.nih.gov/pubmed/37444452
http://dx.doi.org/10.3390/cancers15133341

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