SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model

Acute lymphoblastic leukemia (ALL) is the most common cause of cancer-related death in children. Despite significantly increased chances of cure, especially for high-risk ALL patients, it still represents a poor prognosis for a substantial fraction of patients. Misregulated proteins in central switc...

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Detalles Bibliográficos
Autores principales: Ehm, Patrick, Rietow, Ruth, Wegner, Wiebke, Bußmann, Lara, Kriegs, Malte, Dierck, Kevin, Horn, Stefan, Streichert, Thomas, Horstmann, Martin, Jücker, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341211/
https://www.ncbi.nlm.nih.gov/pubmed/37443832
http://dx.doi.org/10.3390/cells12131798

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