Overview of the Genetic Causes of Hereditary Breast and Ovarian Cancer Syndrome in a Large French Patient Cohort

SIMPLE SUMMARY: Hereditary Breast and Ovarian Cancer syndrome (HBOC) is an inherited trait that predisposes adults to an earlier onset of cancer than the general population. HBOC is an autosomal dominant condition caused by heterozygous mutations in one of the HBOC genes. Pathogenic variants in BRCA...

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Detalles Bibliográficos
Autores principales: Bouras, Ahmed, Guidara, Souhir, Leone, Mélanie, Buisson, Adrien, Martin-Denavit, Tanguy, Dussart, Sophie, Lasset, Christine, Giraud, Sophie, Bonnet-Dupeyron, Marie-Noëlle, Kherraf, Zine-Eddine, Sanlaville, Damien, Fert-Ferrer, Sandra, Lebrun, Marine, Bonadona, Valerie, Calender, Alain, Boutry-Kryza, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341368/
https://www.ncbi.nlm.nih.gov/pubmed/37444530
http://dx.doi.org/10.3390/cancers15133420

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