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Resistance to Chemotherapeutic 5-Fluorouracil Conferred by Modulation of Heterochromatic Integrity through Ino80 Function in Fission Yeast

5-Fluorouracil (5-FU) is a conventional chemotherapeutic drug widely used in clinics worldwide, but development of resistance that compromises responsiveness remains a major hurdle to its efficacy. The mechanism underlying 5-FU resistance is conventionally attributed to the disruption of nucleotide...

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Detalles Bibliográficos
Autores principales:	Lim, Kim Kiat, Koh, Nathaniel Zhi Hao, Zeng, Yi Bing, Chuan, Jun Kai, Raechell, Raechell, Chen, Ee Sin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341484/ https://www.ncbi.nlm.nih.gov/pubmed/37445861 http://dx.doi.org/10.3390/ijms241310687

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