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A Novel Strategy for Screening Tumor-Specific Variable Domain of Heavy-Chain Antibodies

The properties of the variable domain of heavy-chain (VHH) antibodies are particularly relevant in cancer therapy. To isolate tumor cell-specific VHH antibodies, VHH phage libraries were constructed from multiple tumor cells. After enriching the libraries against particular tumor cell lines, a next-...

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Detalles Bibliográficos
Autores principales: Rafique, Abdur, Hichiwa, Genki, Jatnika, Muhammad Feisal, Ito, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341490/
https://www.ncbi.nlm.nih.gov/pubmed/37445977
http://dx.doi.org/10.3390/ijms241310804

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