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The Adaptive Mechanisms and Checkpoint Responses to a Stressed DNA Replication Fork

DNA replication is a tightly controlled process that ensures the faithful duplication of the genome. However, DNA damage arising from both endogenous and exogenous assaults gives rise to DNA replication stress associated with replication fork slowing or stalling. Therefore, protecting the stressed f...

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Detalles Bibliográficos
Autores principales: Saldanha, Joanne, Rageul, Julie, Patel, Jinal A., Kim, Hyungjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341514/
https://www.ncbi.nlm.nih.gov/pubmed/37445667
http://dx.doi.org/10.3390/ijms241310488