Accumulation of Renal Fibrosis in Hyperuricemia Rats Is Attributed to the Recruitment of Mast Cells, Activation of the TGF-β1/Smad2/3 Pathway, and Aggravation of Oxidative Stress

Renal fibrosis is relentlessly progressive and irreversible, and a life-threatening risk. With the continuous intake of a high-purine diet, hyperuricemia has become a health risk factor in addition to hyperglycemia, hypertension, and hyperlipidemia. Hyperuricemia is also an independent risk factor f...

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Detalles Bibliográficos
Autores principales: Zhang, Mingkang, Cui, Ruirui, Zhou, Yan, Ma, Yanrong, Jin, Yongwen, Wang, Lina, Kou, Wen, Wu, Xin’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341566/
https://www.ncbi.nlm.nih.gov/pubmed/37446016
http://dx.doi.org/10.3390/ijms241310839

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