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S-Nitrosylation of Tissue Transglutaminase in Modulating Glycolysis, Oxidative Stress, and Inflammatory Responses in Normal and Indoxyl-Sulfate-Induced Endothelial Cells

Circulating uremic toxin indoxyl sulfate (IS), endothelial cell (EC) dysfunction, and decreased nitric oxide (NO) bioavailability are found in chronic kidney disease patients. NO nitrosylates/denitrosylates a specific protein’s cysteine residue(s), forming S-nitrosothios (SNOs), and the decreased NO...

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Detalles Bibliográficos
Autores principales: Lin, Cheng-Jui, Chiu, Chun Yu, Liao, En-Chih, Wu, Chih-Jen, Chung, Ching-Hu, Greenberg, Charles S., Lai, Thung-S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341700/
https://www.ncbi.nlm.nih.gov/pubmed/37446114
http://dx.doi.org/10.3390/ijms241310935