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Bypass of Abasic Site–Peptide Cross-Links by Human Repair and Translesion DNA Polymerases

DNA–protein cross-links remain the least-studied type of DNA damage. Recently, their repair was shown to involve proteolysis; however, the fate of the peptide remnant attached to DNA is unclear. Particularly, peptide cross-links could interfere with DNA polymerases. Apurinuic/apyrimidinic (AP) sites...

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Detalles Bibliográficos
Autores principales: Yudkina, Anna V., Barmatov, Alexander E., Bulgakov, Nikita A., Boldinova, Elizaveta O., Shilkin, Evgeniy S., Makarova, Alena V., Zharkov, Dmitry O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341727/
https://www.ncbi.nlm.nih.gov/pubmed/37446048
http://dx.doi.org/10.3390/ijms241310877

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