Increased Otoferlin Expression in B Cells Is Associated with Muscle Weakness in Untreated Juvenile Dermatomyositis: A Pilot Study

Otoferlin mRNA expression is increased in JDM patients’ PBMCs and muscle compared to healthy controls. This study aims to evaluate the role of otoferlin in JDM disease pathophysiology and its association with disease activity in untreated children with JDM. A total of 26 untreated JDM (88.5% female,...

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Detalles Bibliográficos
Autores principales: Bukhari, Ameera, Khojah, Amer, Marin, Wilfredo, Khramtsov, Andrey, Khramtsova, Galina, Costin, Christopher, Morgan, Gabrielle, Ramesh, Prathyaya, Klein-Gitelman, Marisa S., Le Poole, I. Caroline, Pachman, Lauren M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341737/
https://www.ncbi.nlm.nih.gov/pubmed/37445728
http://dx.doi.org/10.3390/ijms241310553

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