3-[N,N-Bis(sulfonyl)amino]isoxazolines with Spiro-Annulated or 1,2-Annulated Cyclooctane Rings Inhibit Reproduction of Tick-Borne Encephalitis, Yellow Fever, and West Nile Viruses

Spirocyclic compounds containing heterocyclic moieties represent promising 3D scaffolds for modern drug design. In the search for novel anti-flaviviral agents, we have obtained a series of 3-[N,N-bis(sulfonyl)amino]isoxazolines containing spiro-annulated cyclooctane rings and assessed their antivira...

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Detalles Bibliográficos
Autores principales: Sedenkova, Kseniya N., Sazonov, Artem S., Vasilenko, Dmitry A., Andriasov, Kristian S., Eremenko, Marina G., Grishin, Yuri K., Khvatov, Evgeny V., Goryashchenko, Alexander S., Uvarova, Victoria I., Osolodkin, Dmitry I., Ishmukhametov, Aydar A., Averina, Elena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341786/
https://www.ncbi.nlm.nih.gov/pubmed/37445937
http://dx.doi.org/10.3390/ijms241310758

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