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Research Advances on the Bioactivity of 1,2,3-Triazolium Salts
1,2,3-Triazolium salts have demonstrated significant potential in the fields of medicine and agriculture, exhibiting exceptional antibacterial, antifungal, anticancer, and antileishmanial properties. Moreover, these salts can be utilized as additives or components to produce nano- and fiber-based ma...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341799/ https://www.ncbi.nlm.nih.gov/pubmed/37445872 http://dx.doi.org/10.3390/ijms241310694 |
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author | Song, Jia Lv, Jie Jin, Jiamiao Jin, Zhichao Li, Tingting Wu, Jian |
author_facet | Song, Jia Lv, Jie Jin, Jiamiao Jin, Zhichao Li, Tingting Wu, Jian |
author_sort | Song, Jia |
collection | PubMed |
description | 1,2,3-Triazolium salts have demonstrated significant potential in the fields of medicine and agriculture, exhibiting exceptional antibacterial, antifungal, anticancer, and antileishmanial properties. Moreover, these salts can be utilized as additives or components to produce nano- and fiber-based materials with antibacterial properties. In this review, we summarize several synthetic strategies to obtain 1,2,3-triazolium salts and the structures of 1,2,3-triazolium derivatives with biological activities in the domains of pharmaceuticals, pesticides, and functional materials. Additionally, the structure–activity relationship (SAR) of 1,2,3-triazolium salts with different biological activities has been analyzed. Finally, this review presents the potential applications and prospects of 1,2,3-triazolium salts in the fields of agriculture, medicine, and industrial synthesis. |
format | Online Article Text |
id | pubmed-10341799 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103417992023-07-14 Research Advances on the Bioactivity of 1,2,3-Triazolium Salts Song, Jia Lv, Jie Jin, Jiamiao Jin, Zhichao Li, Tingting Wu, Jian Int J Mol Sci Review 1,2,3-Triazolium salts have demonstrated significant potential in the fields of medicine and agriculture, exhibiting exceptional antibacterial, antifungal, anticancer, and antileishmanial properties. Moreover, these salts can be utilized as additives or components to produce nano- and fiber-based materials with antibacterial properties. In this review, we summarize several synthetic strategies to obtain 1,2,3-triazolium salts and the structures of 1,2,3-triazolium derivatives with biological activities in the domains of pharmaceuticals, pesticides, and functional materials. Additionally, the structure–activity relationship (SAR) of 1,2,3-triazolium salts with different biological activities has been analyzed. Finally, this review presents the potential applications and prospects of 1,2,3-triazolium salts in the fields of agriculture, medicine, and industrial synthesis. MDPI 2023-06-27 /pmc/articles/PMC10341799/ /pubmed/37445872 http://dx.doi.org/10.3390/ijms241310694 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Song, Jia Lv, Jie Jin, Jiamiao Jin, Zhichao Li, Tingting Wu, Jian Research Advances on the Bioactivity of 1,2,3-Triazolium Salts |
title | Research Advances on the Bioactivity of 1,2,3-Triazolium Salts |
title_full | Research Advances on the Bioactivity of 1,2,3-Triazolium Salts |
title_fullStr | Research Advances on the Bioactivity of 1,2,3-Triazolium Salts |
title_full_unstemmed | Research Advances on the Bioactivity of 1,2,3-Triazolium Salts |
title_short | Research Advances on the Bioactivity of 1,2,3-Triazolium Salts |
title_sort | research advances on the bioactivity of 1,2,3-triazolium salts |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341799/ https://www.ncbi.nlm.nih.gov/pubmed/37445872 http://dx.doi.org/10.3390/ijms241310694 |
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