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Research Advances on the Bioactivity of 1,2,3-Triazolium Salts

1,2,3-Triazolium salts have demonstrated significant potential in the fields of medicine and agriculture, exhibiting exceptional antibacterial, antifungal, anticancer, and antileishmanial properties. Moreover, these salts can be utilized as additives or components to produce nano- and fiber-based ma...

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Detalles Bibliográficos
Autores principales: Song, Jia, Lv, Jie, Jin, Jiamiao, Jin, Zhichao, Li, Tingting, Wu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341799/
https://www.ncbi.nlm.nih.gov/pubmed/37445872
http://dx.doi.org/10.3390/ijms241310694
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author Song, Jia
Lv, Jie
Jin, Jiamiao
Jin, Zhichao
Li, Tingting
Wu, Jian
author_facet Song, Jia
Lv, Jie
Jin, Jiamiao
Jin, Zhichao
Li, Tingting
Wu, Jian
author_sort Song, Jia
collection PubMed
description 1,2,3-Triazolium salts have demonstrated significant potential in the fields of medicine and agriculture, exhibiting exceptional antibacterial, antifungal, anticancer, and antileishmanial properties. Moreover, these salts can be utilized as additives or components to produce nano- and fiber-based materials with antibacterial properties. In this review, we summarize several synthetic strategies to obtain 1,2,3-triazolium salts and the structures of 1,2,3-triazolium derivatives with biological activities in the domains of pharmaceuticals, pesticides, and functional materials. Additionally, the structure–activity relationship (SAR) of 1,2,3-triazolium salts with different biological activities has been analyzed. Finally, this review presents the potential applications and prospects of 1,2,3-triazolium salts in the fields of agriculture, medicine, and industrial synthesis.
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spelling pubmed-103417992023-07-14 Research Advances on the Bioactivity of 1,2,3-Triazolium Salts Song, Jia Lv, Jie Jin, Jiamiao Jin, Zhichao Li, Tingting Wu, Jian Int J Mol Sci Review 1,2,3-Triazolium salts have demonstrated significant potential in the fields of medicine and agriculture, exhibiting exceptional antibacterial, antifungal, anticancer, and antileishmanial properties. Moreover, these salts can be utilized as additives or components to produce nano- and fiber-based materials with antibacterial properties. In this review, we summarize several synthetic strategies to obtain 1,2,3-triazolium salts and the structures of 1,2,3-triazolium derivatives with biological activities in the domains of pharmaceuticals, pesticides, and functional materials. Additionally, the structure–activity relationship (SAR) of 1,2,3-triazolium salts with different biological activities has been analyzed. Finally, this review presents the potential applications and prospects of 1,2,3-triazolium salts in the fields of agriculture, medicine, and industrial synthesis. MDPI 2023-06-27 /pmc/articles/PMC10341799/ /pubmed/37445872 http://dx.doi.org/10.3390/ijms241310694 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Song, Jia
Lv, Jie
Jin, Jiamiao
Jin, Zhichao
Li, Tingting
Wu, Jian
Research Advances on the Bioactivity of 1,2,3-Triazolium Salts
title Research Advances on the Bioactivity of 1,2,3-Triazolium Salts
title_full Research Advances on the Bioactivity of 1,2,3-Triazolium Salts
title_fullStr Research Advances on the Bioactivity of 1,2,3-Triazolium Salts
title_full_unstemmed Research Advances on the Bioactivity of 1,2,3-Triazolium Salts
title_short Research Advances on the Bioactivity of 1,2,3-Triazolium Salts
title_sort research advances on the bioactivity of 1,2,3-triazolium salts
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341799/
https://www.ncbi.nlm.nih.gov/pubmed/37445872
http://dx.doi.org/10.3390/ijms241310694
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