Cargando…

Sex Differences in Sphingosine-1-Phosphate Levels Are Dependent on Ceramide Synthase 1 and Ceramidase in Lung Physiology and Tumor Conditions

Sex is a biological variable that can reflect clinical outcomes in terms of quality of life, therapy effectiveness, responsiveness and/or toxicity. Sphingosine-1-phosphate (S1P) is a lipidic mediator whose activity can be influenced by sex. To evaluate whether the S1P axis underlies sex ‘instruction...

Descripción completa

Detalles Bibliográficos
Autores principales:	Terlizzi, Michela, Colarusso, Chiara, Ferraro, Giusy, Falanga, Anna, Monti, Maria Chiara, Somma, Pasquale, De Rosa, Ilaria, Panico, Luigi, Pinto, Aldo, Sorrentino, Rosalinda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341818/ https://www.ncbi.nlm.nih.gov/pubmed/37446018 http://dx.doi.org/10.3390/ijms241310841

Ejemplares similares

Induction of Inflammation Disrupts the Negative Interplay between STING and S1P Axis That Is Observed during Physiological Conditions in the Lung
por: Terlizzi, Michela, et al.
Publicado: (2023)

S1P-Induced TNF-α and IL-6 Release from PBMCs Exacerbates Lung Cancer-Associated Inflammation
por: Terlizzi, Michela, et al.
Publicado: (2022)

IL-1α and IL-1β-producing macrophages populate lung tumor lesions in mice
por: Terlizzi, Michela, et al.
Publicado: (2016)

A lesson from a saboteur: High‐MW kininogen impact in coronavirus‐induced disease 2019
por: Colarusso, Chiara, et al.
Publicado: (2020)

AIM2/IL-1α/TGF-β Axis in PBMCs From Exacerbated Chronic Obstructive Pulmonary Disease (COPD) Patients Is Not Related to COX-2-Dependent Inflammatory Pathway
por: Molino, Antonio, et al.
Publicado: (2019)

Implication of Ceramide, Ceramide 1-Phosphate and Sphingosine 1-Phosphate in Tumorigenesis
por: Gangoiti, Patricia, et al.
Publicado: (2008)

Role of the inflammasome in chronic obstructive pulmonary disease (COPD)
por: Colarusso, Chiara, et al.
Publicado: (2017)

Ceramide and Sphingosine 1-Phosphate in Liver Diseases
por: Park, Woo-Jae, et al.
Publicado: (2020)

The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer
por: Hait, Nitai C., et al.
Publicado: (2017)

AIM2 Inflammasome Activation Leads to IL-1α and TGF-β Release From Exacerbated Chronic Obstructive Pulmonary Disease-Derived Peripheral Blood Mononuclear Cells
por: Colarusso, Chiara, et al.
Publicado: (2019)

Toll-Like Receptor 4 Is Essential for the Expression of Sphingosine-1-Phosphate-Dependent Asthma-Like Disease in Mice
por: Roviezzo, Fiorentina, et al.
Publicado: (2017)

Energy balance and the sphingosine-1-phosphate/ceramide axis
por: Green, Cara, et al.
Publicado: (2017)

Antioxidant and antimicrobial properties of Pelargonium sidoides DC and lactoferrin combination
por: Terlizzi, Michela, et al.
Publicado: (2020)

Post-COVID-19 Patients Who Develop Lung Fibrotic-like Changes Have Lower Circulating Levels of IFN-β but Higher Levels of IL-1α and TGF-β
por: Colarusso, Chiara, et al.
Publicado: (2021)

Identification of a novel subpopulation of Caspase-4 positive non-small cell lung Cancer patients
por: Terlizzi, Michela, et al.
Publicado: (2020)

Sphingolipids and Atherosclerosis: The Dual Role of Ceramide and Sphingosine-1-Phosphate
por: Piccoli, Marco, et al.
Publicado: (2023)

Altered lung tissue lipidomic profile in caspase-4 positive non-small cell lung cancer (NSCLC) patients
por: Terlizzi, Michela, et al.
Publicado: (2020)

Acid Ceramidase Promotes Nuclear Export of PTEN through Sphingosine 1-Phosphate Mediated Akt Signaling
por: Beckham, Thomas H., et al.
Publicado: (2013)

Activation of the Absent in Melanoma 2 Inflammasome in Peripheral Blood Mononuclear Cells From Idiopathic Pulmonary Fibrosis Patients Leads to the Release of Pro-Fibrotic Mediators
por: Terlizzi, Michela, et al.
Publicado: (2018)

Ceramide and Sphingosine-1-Phosphate in Neurodegenerative Disorders and Their Potential Involvement in Therapy
por: Tringali, Cristina, et al.
Publicado: (2022)

Pseudomonas-Derived Ceramidase Induces Production of Inflammatory Mediators from Human Keratinocytes via Sphingosine-1-Phosphate
por: Oizumi, Ami, et al.
Publicado: (2014)

Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma
por: Colarusso, Chiara, et al.
Publicado: (2021)

Genetics of the ceramide/sphingosine-1-phosphate rheostat in blood pressure regulation and hypertension
por: Fenger, Mogens, et al.
Publicado: (2011)

Ceramide in the Molecular Mechanisms of Neuronal Cell Death. The Role of Sphingosine-1-Phosphate
por: Czubowicz, Kinga, et al.
Publicado: (2014)

The Role of Ceramide and Sphingosine-1-Phosphate in Alzheimer’s Disease and Other Neurodegenerative Disorders
por: Czubowicz, Kinga, et al.
Publicado: (2019)

Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients
por: Myśliwiec, Hanna, et al.
Publicado: (2016)

Sphingosine‐1‐phosphate/TGF‐β axis drives epithelial mesenchymal transition in asthma‐like disease
por: Riemma, Maria A., et al.
Publicado: (2022)

Activation of the AIM2 Receptor in Circulating Cells of Post-COVID-19 Patients With Signs of Lung Fibrosis Is Associated With the Release of IL-1α, IFN-α and TGF-β
por: Colarusso, Chiara, et al.
Publicado: (2022)

Sex Differences in Cardiovascular Diseases: A Matter of Estrogens, Ceramides, and Sphingosine 1-Phosphate
por: Arosio, Beatrice, et al.
Publicado: (2022)

The Inhibition of Caspase-1- Does Not Revert Particulate Matter (PM)-Induced Lung Immunesuppression in Mice
por: Colarusso, Chiara, et al.
Publicado: (2019)

The imbalance in the aortic ceramide/sphingosine-1-phosphate rheostat in ovariectomized rats and the preventive effect of estrogen
por: Li, Yao, et al.
Publicado: (2020)

Serum sphingolipidomic analyses reveal an upregulation of C16- ceramide and sphingosine-1-phosphate in hepatocellular carcinoma
por: Grammatikos, Georgios, et al.
Publicado: (2016)

A Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury
por: Ueda, Norishi
Publicado: (2022)

Ceramide and ceramide 1-phosphate in health and disease
por: Arana, Lide, et al.
Publicado: (2010)

Alkaline Ceramidase Mediates the Oxidative Stress Response in Drosophila melanogaster Through Sphingosine
por: Zhang, Chun-Hong, et al.
Publicado: (2019)

Interaction of microRNAs with sphingosine kinases, sphingosine-1 phosphate, and sphingosine-1 phosphate receptors in cancer
por: Xu, Guangmeng, et al.
Publicado: (2021)

Correction: Circulating and tumor-associated caspase-4: a novel diagnostic and prognostic biomarker for non-small cell lung cancer
por: Terlizzi, Michela, et al.
Publicado: (2018)

Chronic Obstructive Pulmonary Disease-Derived Circulating Cells Release IL-18 and IL-33 under Ultrafine Particulate Matter Exposure in a Caspase-1/8-Independent Manner
por: De Falco, Gianluigi, et al.
Publicado: (2017)

Circulating and tumor-associated caspase-4: a novel diagnostic and prognostic biomarker for non-small cell lung cancer
por: Terlizzi, Michela, et al.
Publicado: (2018)

Inverse Correlation Between Plasma Sphingosine-1-Phosphate and Ceramide Concentrations in Septic Patients and Their Utility in Predicting Mortality
por: Wu, Xiaoliang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4uiq9hcvisboa3eao06g7aulu9