Reduced Levels of Selenium and Thioredoxin Reductase in the Thoracic Aorta Could Contribute to Aneurysm Formation in Patients with Marfan Syndrome

Marfan syndrome (MFS) is an autosomal dominant disorder caused by a heterozygous mutation of the FBN1 gene. MFS patients present oxidative stress that disturbs redox homeostasis. Redox homeostasis depends in part on the enzymatic antioxidant system, which includes thioredoxin reductase (TrxR) and gl...

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Detalles Bibliográficos
Autores principales: Soto, María Elena, Pérez-Torres, Israel, Manzano-Pech, Linaloe, Soria-Castro, Elizabeth, Morales-Marín, Almilcar, Ramírez-Marroquín, Edgar Samuel, Martínez-Hernández, Humberto, Herrera-Alarcón, Valentín, Guarner-Lans, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341829/
https://www.ncbi.nlm.nih.gov/pubmed/37445606
http://dx.doi.org/10.3390/ijms241310429

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