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Induction of Hepcidin Expression in the Renal Cortex of Sickle Cell Disease Mice
In patients with sickle cell disease (SCD), chronic hemolysis and frequent blood transfusions cause iron overload and accumulation in the kidneys. The iron deposition is found in the renal cortex and correlates with the severity of hemolysis. In this study, we observed a significant accumulation of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341858/ https://www.ncbi.nlm.nih.gov/pubmed/37445980 http://dx.doi.org/10.3390/ijms241310806 |