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IL-22 Is Deleterious along with IL-17 in Allergic Asthma but Is Not Detrimental in the Comorbidity Asthma and Acute Pneumonia

There is evidence that IL-22 and IL-17 participate in the pathogenesis of allergic asthma. To investigate the role of IL-22, we used IL-22 deficient mice (IL-22 KO) sensitized and challenged with ovalbumin (OVA) and compared with wild type (WT) animals exposed to OVA. IL-22 KO animals exposed to OVA...

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Detalles Bibliográficos
Autores principales: Goulart, Amanda, Boko, Mèdéton Mahoussi Michaël, Martins, Nubia Sabrina, Gembre, Ana Flávia, de Oliveira, Rômulo Silva, Palma-Albornoz, Sandra Patrícia, Bertolini, Thais, Ribolla, Paulo Eduardo Martins, Ramalho, Leandra Naira Zambelli, Fraga-Silva, Thais Fernanda de Campos, Bonato, Vânia Luiza Deperon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341917/
https://www.ncbi.nlm.nih.gov/pubmed/37445595
http://dx.doi.org/10.3390/ijms241310418