Using Human ‘Personalized’ Cybrids to Identify Drugs/Agents That Can Regulate Chronic Lymphoblastic Leukemia Mitochondrial Dysfunction

This study uses personalized chronic lymphoblastic leukemia (CLL) cybrid cells to test various drugs/agents designed to improve mitochondrial function and cell longevity. Age-matched control (NL) and CLL cybrids were created. The NL and CLL cybrids were treated with ibrutinib (Ibr-10 μM), mitochondr...

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Detalles Bibliográficos
Autores principales: Singh, Lata, Atilano, Shari, Chwa, Marilyn, Singh, Mithalesh K., Ozgul, Mustafa, Nesburn, Anthony, Kenney, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341973/
https://www.ncbi.nlm.nih.gov/pubmed/37446202
http://dx.doi.org/10.3390/ijms241311025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341973/
https://www.ncbi.nlm.nih.gov/pubmed/37446202
http://dx.doi.org/10.3390/ijms241311025

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