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A2BAR Antagonism Decreases the Glomerular Expression and Secretion of Chemoattractants for Monocytes and the Pro-Fibrotic M2 Macrophages Polarization during Diabetic Nephropathy

Some chemoattractants and leukocytes such as M1 and M2 macrophages are known to be involved in the development of glomerulosclerosis during diabetic nephropathy (DN). In the course of diabetes, an altered and defective cellular metabolism leads to the increase in adenosine levels, and thus to change...

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Detalles Bibliográficos
Autores principales: Torres-Arévalo, Ángelo, Nahuelpán, Yéssica, Muñoz, Katherin, Jara, Claudia, Cappelli, Claudio, Taracha-Wiśniewska, Agnieszka, Quezada-Monrás, Claudia, Martín, Rody San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342004/
https://www.ncbi.nlm.nih.gov/pubmed/37446007
http://dx.doi.org/10.3390/ijms241310829