Analysis of the Mutational Landscape of Osteosarcomas Identifies Genes Related to Metastasis and Prognosis and Disrupted Biological Pathways of Immune Response and Bone Development

Osteosarcoma (OS) is the most prevalent type of bone tumor, but slow progress has been achieved in disentangling the full set of genomic events involved in its initiation and progression. We assessed by NGS the mutational spectrum of 28 primary OSs from Brazilian patients, and identified 445 potenti...

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Detalles Bibliográficos
Autores principales: Pires, Sara Ferreira, de Barros, Juliana Sobral, da Costa, Silvia Souza, do Carmo, Gabriel Bandeira, Scliar, Marília de Oliveira, Lengert, André van Helvoort, Boldrini, Érica, da Silva, Sandra Regini Morini, Vidal, Daniel Onofre, Maschietto, Mariana, Krepischi, Ana Cristina Victorino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342084/
https://www.ncbi.nlm.nih.gov/pubmed/37445641
http://dx.doi.org/10.3390/ijms241310463

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