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Comparative Proteomic Analysis of Toxoplasma gondii RH Wild-Type and Four SRS29B (SAG1) Knock-Out Clones Reveals Significant Differences between Individual Strains

In T. gondii, as well as in other model organisms, gene knock-out using CRISPR-Cas9 is a suitable tool to identify the role of specific genes. The general consensus implies that only the gene of interest is affected by the knock-out. Is this really the case? In a previous study, we generated knock-o...

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Detalles Bibliográficos
Autores principales: Hänggeli, Kai Pascal Alexander, Hemphill, Andrew, Müller, Norbert, Heller, Manfred, Uldry, Anne-Christine, Braga-Lagache, Sophie, Müller, Joachim, Boubaker, Ghalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342146/
https://www.ncbi.nlm.nih.gov/pubmed/37445632
http://dx.doi.org/10.3390/ijms241310454