Site-Specific RNA Editing of Stop Mutations in the CFTR mRNA of Human Bronchial Cultured Cells

It is reported that about 10% of cystic fibrosis (CF) patients worldwide have nonsense (stop) mutations in the CFTR gene, which cause the premature termination of CFTR protein synthesis, leading to a truncated and non-functional protein. To address this issue, we investigated the possibility of resc...

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Detalles Bibliográficos
Autores principales: Chiavetta, Roberta F., Titoli, Simona, Barra, Viviana, Cancemi, Patrizia, Melfi, Raffaella, Di Leonardo, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342162/
https://www.ncbi.nlm.nih.gov/pubmed/37446121
http://dx.doi.org/10.3390/ijms241310940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342162/
https://www.ncbi.nlm.nih.gov/pubmed/37446121
http://dx.doi.org/10.3390/ijms241310940

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