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New Insights and Potential Therapeutic Interventions in Metabolic Diseases
Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this revi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342188/ https://www.ncbi.nlm.nih.gov/pubmed/37445852 http://dx.doi.org/10.3390/ijms241310672 |
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author | Clemente-Suárez, Vicente Javier Martín-Rodríguez, Alexandra Redondo-Flórez, Laura López-Mora, Clara Yáñez-Sepúlveda, Rodrigo Tornero-Aguilera, José Francisco |
author_facet | Clemente-Suárez, Vicente Javier Martín-Rodríguez, Alexandra Redondo-Flórez, Laura López-Mora, Clara Yáñez-Sepúlveda, Rodrigo Tornero-Aguilera, José Francisco |
author_sort | Clemente-Suárez, Vicente Javier |
collection | PubMed |
description | Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this review, we discussed the rise of metabolic diseases, especially in Western countries, the genetical, psychological, and behavioral basis of metabolic diseases, the role of nutrition and physical activity in the development of metabolic diseases, the role of single-cell transcriptomics, gut microbiota, epigenetics, advanced imaging techniques, and cell-based therapies in metabolic diseases. Finally, practical applications derived from this information are made. |
format | Online Article Text |
id | pubmed-10342188 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103421882023-07-14 New Insights and Potential Therapeutic Interventions in Metabolic Diseases Clemente-Suárez, Vicente Javier Martín-Rodríguez, Alexandra Redondo-Flórez, Laura López-Mora, Clara Yáñez-Sepúlveda, Rodrigo Tornero-Aguilera, José Francisco Int J Mol Sci Review Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this review, we discussed the rise of metabolic diseases, especially in Western countries, the genetical, psychological, and behavioral basis of metabolic diseases, the role of nutrition and physical activity in the development of metabolic diseases, the role of single-cell transcriptomics, gut microbiota, epigenetics, advanced imaging techniques, and cell-based therapies in metabolic diseases. Finally, practical applications derived from this information are made. MDPI 2023-06-26 /pmc/articles/PMC10342188/ /pubmed/37445852 http://dx.doi.org/10.3390/ijms241310672 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Clemente-Suárez, Vicente Javier Martín-Rodríguez, Alexandra Redondo-Flórez, Laura López-Mora, Clara Yáñez-Sepúlveda, Rodrigo Tornero-Aguilera, José Francisco New Insights and Potential Therapeutic Interventions in Metabolic Diseases |
title | New Insights and Potential Therapeutic Interventions in Metabolic Diseases |
title_full | New Insights and Potential Therapeutic Interventions in Metabolic Diseases |
title_fullStr | New Insights and Potential Therapeutic Interventions in Metabolic Diseases |
title_full_unstemmed | New Insights and Potential Therapeutic Interventions in Metabolic Diseases |
title_short | New Insights and Potential Therapeutic Interventions in Metabolic Diseases |
title_sort | new insights and potential therapeutic interventions in metabolic diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342188/ https://www.ncbi.nlm.nih.gov/pubmed/37445852 http://dx.doi.org/10.3390/ijms241310672 |
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