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New Insights and Potential Therapeutic Interventions in Metabolic Diseases

Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this revi...

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Autores principales: Clemente-Suárez, Vicente Javier, Martín-Rodríguez, Alexandra, Redondo-Flórez, Laura, López-Mora, Clara, Yáñez-Sepúlveda, Rodrigo, Tornero-Aguilera, José Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342188/
https://www.ncbi.nlm.nih.gov/pubmed/37445852
http://dx.doi.org/10.3390/ijms241310672
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author Clemente-Suárez, Vicente Javier
Martín-Rodríguez, Alexandra
Redondo-Flórez, Laura
López-Mora, Clara
Yáñez-Sepúlveda, Rodrigo
Tornero-Aguilera, José Francisco
author_facet Clemente-Suárez, Vicente Javier
Martín-Rodríguez, Alexandra
Redondo-Flórez, Laura
López-Mora, Clara
Yáñez-Sepúlveda, Rodrigo
Tornero-Aguilera, José Francisco
author_sort Clemente-Suárez, Vicente Javier
collection PubMed
description Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this review, we discussed the rise of metabolic diseases, especially in Western countries, the genetical, psychological, and behavioral basis of metabolic diseases, the role of nutrition and physical activity in the development of metabolic diseases, the role of single-cell transcriptomics, gut microbiota, epigenetics, advanced imaging techniques, and cell-based therapies in metabolic diseases. Finally, practical applications derived from this information are made.
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spelling pubmed-103421882023-07-14 New Insights and Potential Therapeutic Interventions in Metabolic Diseases Clemente-Suárez, Vicente Javier Martín-Rodríguez, Alexandra Redondo-Flórez, Laura López-Mora, Clara Yáñez-Sepúlveda, Rodrigo Tornero-Aguilera, José Francisco Int J Mol Sci Review Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this review, we discussed the rise of metabolic diseases, especially in Western countries, the genetical, psychological, and behavioral basis of metabolic diseases, the role of nutrition and physical activity in the development of metabolic diseases, the role of single-cell transcriptomics, gut microbiota, epigenetics, advanced imaging techniques, and cell-based therapies in metabolic diseases. Finally, practical applications derived from this information are made. MDPI 2023-06-26 /pmc/articles/PMC10342188/ /pubmed/37445852 http://dx.doi.org/10.3390/ijms241310672 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Clemente-Suárez, Vicente Javier
Martín-Rodríguez, Alexandra
Redondo-Flórez, Laura
López-Mora, Clara
Yáñez-Sepúlveda, Rodrigo
Tornero-Aguilera, José Francisco
New Insights and Potential Therapeutic Interventions in Metabolic Diseases
title New Insights and Potential Therapeutic Interventions in Metabolic Diseases
title_full New Insights and Potential Therapeutic Interventions in Metabolic Diseases
title_fullStr New Insights and Potential Therapeutic Interventions in Metabolic Diseases
title_full_unstemmed New Insights and Potential Therapeutic Interventions in Metabolic Diseases
title_short New Insights and Potential Therapeutic Interventions in Metabolic Diseases
title_sort new insights and potential therapeutic interventions in metabolic diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342188/
https://www.ncbi.nlm.nih.gov/pubmed/37445852
http://dx.doi.org/10.3390/ijms241310672
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