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From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital

Background: The coronavirus disease 2019 (COVID-19) pandemic began in Brazil on 26 February 2020. By 6 May 2023, 37.4 million cases had been confirmed, causing 701 thousand deaths in the country. We aimed to describe the epidemiological profile and clinical development of COVID-19 cases among the em...

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Autores principales: da Silva, Marielen Ribeiro Tavares, Costa, Ana Paula, da Luz, Amanda Almeida, Pelaio, Caio Henrique, Cruz, Felipe Baleche, Steil, Giovanna Fischer, Giamberardino, Heloisa Ihle Garcia, Prando, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342319/
https://www.ncbi.nlm.nih.gov/pubmed/37445359
http://dx.doi.org/10.3390/jcm12134325
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author da Silva, Marielen Ribeiro Tavares
Costa, Ana Paula
da Luz, Amanda Almeida
Pelaio, Caio Henrique
Cruz, Felipe Baleche
Steil, Giovanna Fischer
Giamberardino, Heloisa Ihle Garcia
Prando, Carolina
author_facet da Silva, Marielen Ribeiro Tavares
Costa, Ana Paula
da Luz, Amanda Almeida
Pelaio, Caio Henrique
Cruz, Felipe Baleche
Steil, Giovanna Fischer
Giamberardino, Heloisa Ihle Garcia
Prando, Carolina
author_sort da Silva, Marielen Ribeiro Tavares
collection PubMed
description Background: The coronavirus disease 2019 (COVID-19) pandemic began in Brazil on 26 February 2020. By 6 May 2023, 37.4 million cases had been confirmed, causing 701 thousand deaths in the country. We aimed to describe the epidemiological profile and clinical development of COVID-19 cases among the employees of a health institution, from acute infection to long COVID. Methods: This was a longitudinal study using a retrospective and prospective approach via questionnaires referring to epidemiological investigation, which was the inclusion criteria, and about long-term symptoms. Results: A total of 809 employees were detected with SARS-CoV-2 infection via RT-PCR, 466 of them answered the epidemiological investigation, and 101 completed the Long COVID Symptom Questionnaire. The most commonly affected employees were women (88.6%) working in patient care (68.6%). Headache, myalgia, cough, odynophagia, and runny nose were the most frequent symptoms. Only three employees (0.6%) required hospitalization, while the other employees required outpatient management due to mild symptoms. We identified 19 (4.1%) cases of reinfection, and 42 (41.6%) employees reported long-term symptoms, such as myalgia, dyspnea, and headache. Conclusions: Although most cases were mild with good outcomes, long COVID cases identified are noteworthy, as these symptoms may impact quality of life even months after SARS-CoV-2 infection.
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spelling pubmed-103423192023-07-14 From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital da Silva, Marielen Ribeiro Tavares Costa, Ana Paula da Luz, Amanda Almeida Pelaio, Caio Henrique Cruz, Felipe Baleche Steil, Giovanna Fischer Giamberardino, Heloisa Ihle Garcia Prando, Carolina J Clin Med Article Background: The coronavirus disease 2019 (COVID-19) pandemic began in Brazil on 26 February 2020. By 6 May 2023, 37.4 million cases had been confirmed, causing 701 thousand deaths in the country. We aimed to describe the epidemiological profile and clinical development of COVID-19 cases among the employees of a health institution, from acute infection to long COVID. Methods: This was a longitudinal study using a retrospective and prospective approach via questionnaires referring to epidemiological investigation, which was the inclusion criteria, and about long-term symptoms. Results: A total of 809 employees were detected with SARS-CoV-2 infection via RT-PCR, 466 of them answered the epidemiological investigation, and 101 completed the Long COVID Symptom Questionnaire. The most commonly affected employees were women (88.6%) working in patient care (68.6%). Headache, myalgia, cough, odynophagia, and runny nose were the most frequent symptoms. Only three employees (0.6%) required hospitalization, while the other employees required outpatient management due to mild symptoms. We identified 19 (4.1%) cases of reinfection, and 42 (41.6%) employees reported long-term symptoms, such as myalgia, dyspnea, and headache. Conclusions: Although most cases were mild with good outcomes, long COVID cases identified are noteworthy, as these symptoms may impact quality of life even months after SARS-CoV-2 infection. MDPI 2023-06-27 /pmc/articles/PMC10342319/ /pubmed/37445359 http://dx.doi.org/10.3390/jcm12134325 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
da Silva, Marielen Ribeiro Tavares
Costa, Ana Paula
da Luz, Amanda Almeida
Pelaio, Caio Henrique
Cruz, Felipe Baleche
Steil, Giovanna Fischer
Giamberardino, Heloisa Ihle Garcia
Prando, Carolina
From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital
title From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital
title_full From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital
title_fullStr From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital
title_full_unstemmed From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital
title_short From Acute Phase to Long COVID: A Cross-Sectional Study of the Epidemiological Profile and Clinical Evaluation of SARS-CoV-2 Infection in Employees at a Pediatric Hospital
title_sort from acute phase to long covid: a cross-sectional study of the epidemiological profile and clinical evaluation of sars-cov-2 infection in employees at a pediatric hospital
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342319/
https://www.ncbi.nlm.nih.gov/pubmed/37445359
http://dx.doi.org/10.3390/jcm12134325
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