Lamin A/C Ablation Restricted to Vascular Smooth Muscle Cells, Cardiomyocytes, and Cardiac Fibroblasts Causes Cardiac and Vascular Dysfunction

Mutations in the LMNA gene (encoding lamin A/C proteins) cause several human cardiac diseases, including dilated cardiomyopathies (LMNA-DCM). The main clinical risks in LMNA-DCM patients are sudden cardiac death and progressive left ventricular ejection fraction deterioration, and therefore most hum...

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Detalles Bibliográficos
Autores principales: Del Monte-Monge, Alberto, Ruiz-Polo de Lara, Íñigo, Gonzalo, Pilar, Espinós-Estévez, Carla, González-Amor, María, de la Fuente-Pérez, Miguel, Andrés-Manzano, María J., Fanjul, Víctor, Gimeno, Juan R., Barriales-Villa, Roberto, Dorado, Beatriz, Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342548/
https://www.ncbi.nlm.nih.gov/pubmed/37446344
http://dx.doi.org/10.3390/ijms241311172

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