A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice

Antiplatelet therapy plays a crucial role in a number of cardiovascular disorders. We currently have a range of antiplatelet agents in our armamentarium. In this review, we aim to summarise the common antiplatelet agents currently available, and their use in clinic practice. We not only highlight re...

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Detalles Bibliográficos
Autores principales: Arockiam, Sacchin, Staniforth, Brittany, Kepreotis, Sacha, Maznyczka, Annette, Bulluck, Heerajnarain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342577/
https://www.ncbi.nlm.nih.gov/pubmed/37446310
http://dx.doi.org/10.3390/ijms241311132
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author Arockiam, Sacchin
Staniforth, Brittany
Kepreotis, Sacha
Maznyczka, Annette
Bulluck, Heerajnarain
author_facet Arockiam, Sacchin
Staniforth, Brittany
Kepreotis, Sacha
Maznyczka, Annette
Bulluck, Heerajnarain
author_sort Arockiam, Sacchin
collection PubMed
description Antiplatelet therapy plays a crucial role in a number of cardiovascular disorders. We currently have a range of antiplatelet agents in our armamentarium. In this review, we aim to summarise the common antiplatelet agents currently available, and their use in clinic practice. We not only highlight recent trials exploring antiplatelet therapy in atherosclerotic cardiovascular disease, but also in trials related to transcatheter aortic valve implantation and coronavirus disease 2019. Inevitably, the antithrombotic benefits of these drugs are accompanied by an increase in bleeding complications. Therefore, an individualised approach to weighing each patient’s thrombotic risk versus bleeding risk is imperative, in order to improve clinical outcomes.
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spelling pubmed-103425772023-07-14 A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice Arockiam, Sacchin Staniforth, Brittany Kepreotis, Sacha Maznyczka, Annette Bulluck, Heerajnarain Int J Mol Sci Review Antiplatelet therapy plays a crucial role in a number of cardiovascular disorders. We currently have a range of antiplatelet agents in our armamentarium. In this review, we aim to summarise the common antiplatelet agents currently available, and their use in clinic practice. We not only highlight recent trials exploring antiplatelet therapy in atherosclerotic cardiovascular disease, but also in trials related to transcatheter aortic valve implantation and coronavirus disease 2019. Inevitably, the antithrombotic benefits of these drugs are accompanied by an increase in bleeding complications. Therefore, an individualised approach to weighing each patient’s thrombotic risk versus bleeding risk is imperative, in order to improve clinical outcomes. MDPI 2023-07-05 /pmc/articles/PMC10342577/ /pubmed/37446310 http://dx.doi.org/10.3390/ijms241311132 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Arockiam, Sacchin
Staniforth, Brittany
Kepreotis, Sacha
Maznyczka, Annette
Bulluck, Heerajnarain
A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice
title A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice
title_full A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice
title_fullStr A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice
title_full_unstemmed A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice
title_short A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice
title_sort contemporary review of antiplatelet therapies in current clinical practice
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342577/
https://www.ncbi.nlm.nih.gov/pubmed/37446310
http://dx.doi.org/10.3390/ijms241311132
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