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COVID-19 and Fatty Liver Disorders

In late 2019, the world was shaken by the COVID-19 pandemic. Severe Acute Respiratory Syndrome Coronavirus—2 (SARS-CoV-2) infection became one of the main causes of illness and hospitalization worldwide, especially in subjects with metabolic comorbidities such as obesity, diabetes, or liver disease....

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Autores principales: Guarino, Maria, Cossiga, Valentina, Cutolo, Francesco Maria, Attanasio, Maria Rosaria, Lieto, Raffaele, Morisco, Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342635/
https://www.ncbi.nlm.nih.gov/pubmed/37445349
http://dx.doi.org/10.3390/jcm12134316
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author Guarino, Maria
Cossiga, Valentina
Cutolo, Francesco Maria
Attanasio, Maria Rosaria
Lieto, Raffaele
Morisco, Filomena
author_facet Guarino, Maria
Cossiga, Valentina
Cutolo, Francesco Maria
Attanasio, Maria Rosaria
Lieto, Raffaele
Morisco, Filomena
author_sort Guarino, Maria
collection PubMed
description In late 2019, the world was shaken by the COVID-19 pandemic. Severe Acute Respiratory Syndrome Coronavirus—2 (SARS-CoV-2) infection became one of the main causes of illness and hospitalization worldwide, especially in subjects with metabolic comorbidities such as obesity, diabetes, or liver disease. This scenario crosses with the metabolic liver disorders’ “pandemic”, caused by the exponential spreading of non-alcoholic fatty liver disease, which is now the most prevalent cause of chronic liver disease (CLD). The aim of this review is to analyze the key factors of the relationship between COVID-19 and the spectrum of fatty liver disorders (FLD), in terms of molecular mechanisms and clinical presentation which can predict a more severe course of the infection. In addition, this review will face the change in management of FLD during pandemics, with a central role of telemedicine, and the role of other interventions in preventing and treating severe infection in these subjects.
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spelling pubmed-103426352023-07-14 COVID-19 and Fatty Liver Disorders Guarino, Maria Cossiga, Valentina Cutolo, Francesco Maria Attanasio, Maria Rosaria Lieto, Raffaele Morisco, Filomena J Clin Med Review In late 2019, the world was shaken by the COVID-19 pandemic. Severe Acute Respiratory Syndrome Coronavirus—2 (SARS-CoV-2) infection became one of the main causes of illness and hospitalization worldwide, especially in subjects with metabolic comorbidities such as obesity, diabetes, or liver disease. This scenario crosses with the metabolic liver disorders’ “pandemic”, caused by the exponential spreading of non-alcoholic fatty liver disease, which is now the most prevalent cause of chronic liver disease (CLD). The aim of this review is to analyze the key factors of the relationship between COVID-19 and the spectrum of fatty liver disorders (FLD), in terms of molecular mechanisms and clinical presentation which can predict a more severe course of the infection. In addition, this review will face the change in management of FLD during pandemics, with a central role of telemedicine, and the role of other interventions in preventing and treating severe infection in these subjects. MDPI 2023-06-27 /pmc/articles/PMC10342635/ /pubmed/37445349 http://dx.doi.org/10.3390/jcm12134316 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Guarino, Maria
Cossiga, Valentina
Cutolo, Francesco Maria
Attanasio, Maria Rosaria
Lieto, Raffaele
Morisco, Filomena
COVID-19 and Fatty Liver Disorders
title COVID-19 and Fatty Liver Disorders
title_full COVID-19 and Fatty Liver Disorders
title_fullStr COVID-19 and Fatty Liver Disorders
title_full_unstemmed COVID-19 and Fatty Liver Disorders
title_short COVID-19 and Fatty Liver Disorders
title_sort covid-19 and fatty liver disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342635/
https://www.ncbi.nlm.nih.gov/pubmed/37445349
http://dx.doi.org/10.3390/jcm12134316
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