Formation of Transient Protein Aggregate-like Centers Is a General Strategy Postponing Degradation of Misfolded Intermediates

When misfolded intermediates accumulate during heat shock, the protein quality control system promotes cellular adaptation strategies. In Schizosaccharomyces pombe, thermo-sensitive proteins assemble upon stress into protein aggregate-like centers, PACs, to escape from degradation. The role of this...

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Detalles Bibliográficos
Autores principales: Boronat, Susanna, Cabrera, Margarita, Vega, Montserrat, Alcalá, Jorge, Salas-Pino, Silvia, Daga, Rafael R., Ayté, José, Hidalgo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342647/
https://www.ncbi.nlm.nih.gov/pubmed/37446379
http://dx.doi.org/10.3390/ijms241311202

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