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The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta †

(1) Background: Despite optimal surgical therapy, replacement of the ascending aorta leads to a significant reduction in the quality of life (QoL). However, an optimal result includes maintaining and improving the QoL. The aim of our study was to evaluate the long-term outcome and the QoL in patient...

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Autores principales: Hamiko, Marwan, Jahnel, Katja, Rogaczewski, Julia, Schafigh, Myriam, Silaschi, Miriam, Spaeth, Andre, Velten, Markus, Roell, Wilhelm, Ahmad, Ali El-Sayed, Bakhtiary, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342701/
https://www.ncbi.nlm.nih.gov/pubmed/37445533
http://dx.doi.org/10.3390/jcm12134498
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author Hamiko, Marwan
Jahnel, Katja
Rogaczewski, Julia
Schafigh, Myriam
Silaschi, Miriam
Spaeth, Andre
Velten, Markus
Roell, Wilhelm
Ahmad, Ali El-Sayed
Bakhtiary, Farhad
author_facet Hamiko, Marwan
Jahnel, Katja
Rogaczewski, Julia
Schafigh, Myriam
Silaschi, Miriam
Spaeth, Andre
Velten, Markus
Roell, Wilhelm
Ahmad, Ali El-Sayed
Bakhtiary, Farhad
author_sort Hamiko, Marwan
collection PubMed
description (1) Background: Despite optimal surgical therapy, replacement of the ascending aorta leads to a significant reduction in the quality of life (QoL). However, an optimal result includes maintaining and improving the QoL. The aim of our study was to evaluate the long-term outcome and the QoL in patients with aneurysms in the ascending aorta; (2) Methods: Between 2014 and 2020, 121 consecutive patients who underwent replacement of the ascending aorta were included in this study. Acute aortic pathologies were excluded. A standard short form (SF)-36 questionnaire was sent to the 112 survivors. According to the surgical procedure, patients were divided into two groups (A: supracoronary replacement of the aorta, n = 35 and B: Wheat-, David- or Bentall-procedures, n = 86). The QoL was compared within these groups and to the normal population, including myocardial infarction (MI), coronary artery disease (CAD) and cancer (CAN) patients; (3) Results: 83 patients were males (68.6%) with a mean age of 62.0 ± 12.5 years. Early postoperative outcomes showed comparable results between groups A and B, with a higher re-thoracotomy rate in B (A: 0.0% vs. B: 22.1%, p = 0.002). The 30-day mortality was zero. Overall, mortality during the follow-up was 7.4%. The SF-36 showed a significant decay in both the Physical (PCS) and Mental Component Summary (MCS) in comparison to the normal population (PCS: 41.1 vs. 48.4, p < 0.001; MCS: 42.1 vs. 50.9, p < 0.001) but without significant difference between both groups. Compared to the MI and CAD patients, significantly higher PCS but lower MCS scores were detected (p < 0.05); (4) Conclusions: Replacement of the ascending aorta shows low risk regarding the operative and postoperative outcomes with satisfying long-term results in the QoL. The extent of the surgical procedure does not influence the postoperative QoL.
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spelling pubmed-103427012023-07-14 The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta † Hamiko, Marwan Jahnel, Katja Rogaczewski, Julia Schafigh, Myriam Silaschi, Miriam Spaeth, Andre Velten, Markus Roell, Wilhelm Ahmad, Ali El-Sayed Bakhtiary, Farhad J Clin Med Article (1) Background: Despite optimal surgical therapy, replacement of the ascending aorta leads to a significant reduction in the quality of life (QoL). However, an optimal result includes maintaining and improving the QoL. The aim of our study was to evaluate the long-term outcome and the QoL in patients with aneurysms in the ascending aorta; (2) Methods: Between 2014 and 2020, 121 consecutive patients who underwent replacement of the ascending aorta were included in this study. Acute aortic pathologies were excluded. A standard short form (SF)-36 questionnaire was sent to the 112 survivors. According to the surgical procedure, patients were divided into two groups (A: supracoronary replacement of the aorta, n = 35 and B: Wheat-, David- or Bentall-procedures, n = 86). The QoL was compared within these groups and to the normal population, including myocardial infarction (MI), coronary artery disease (CAD) and cancer (CAN) patients; (3) Results: 83 patients were males (68.6%) with a mean age of 62.0 ± 12.5 years. Early postoperative outcomes showed comparable results between groups A and B, with a higher re-thoracotomy rate in B (A: 0.0% vs. B: 22.1%, p = 0.002). The 30-day mortality was zero. Overall, mortality during the follow-up was 7.4%. The SF-36 showed a significant decay in both the Physical (PCS) and Mental Component Summary (MCS) in comparison to the normal population (PCS: 41.1 vs. 48.4, p < 0.001; MCS: 42.1 vs. 50.9, p < 0.001) but without significant difference between both groups. Compared to the MI and CAD patients, significantly higher PCS but lower MCS scores were detected (p < 0.05); (4) Conclusions: Replacement of the ascending aorta shows low risk regarding the operative and postoperative outcomes with satisfying long-term results in the QoL. The extent of the surgical procedure does not influence the postoperative QoL. MDPI 2023-07-05 /pmc/articles/PMC10342701/ /pubmed/37445533 http://dx.doi.org/10.3390/jcm12134498 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hamiko, Marwan
Jahnel, Katja
Rogaczewski, Julia
Schafigh, Myriam
Silaschi, Miriam
Spaeth, Andre
Velten, Markus
Roell, Wilhelm
Ahmad, Ali El-Sayed
Bakhtiary, Farhad
The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta †
title The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta †
title_full The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta †
title_fullStr The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta †
title_full_unstemmed The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta †
title_short The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta †
title_sort long-term outcome and quality of life after replacement of the ascending aorta †
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342701/
https://www.ncbi.nlm.nih.gov/pubmed/37445533
http://dx.doi.org/10.3390/jcm12134498
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