Cargando…
The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta †
(1) Background: Despite optimal surgical therapy, replacement of the ascending aorta leads to a significant reduction in the quality of life (QoL). However, an optimal result includes maintaining and improving the QoL. The aim of our study was to evaluate the long-term outcome and the QoL in patient...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342701/ https://www.ncbi.nlm.nih.gov/pubmed/37445533 http://dx.doi.org/10.3390/jcm12134498 |
_version_ | 1785072562180456448 |
---|---|
author | Hamiko, Marwan Jahnel, Katja Rogaczewski, Julia Schafigh, Myriam Silaschi, Miriam Spaeth, Andre Velten, Markus Roell, Wilhelm Ahmad, Ali El-Sayed Bakhtiary, Farhad |
author_facet | Hamiko, Marwan Jahnel, Katja Rogaczewski, Julia Schafigh, Myriam Silaschi, Miriam Spaeth, Andre Velten, Markus Roell, Wilhelm Ahmad, Ali El-Sayed Bakhtiary, Farhad |
author_sort | Hamiko, Marwan |
collection | PubMed |
description | (1) Background: Despite optimal surgical therapy, replacement of the ascending aorta leads to a significant reduction in the quality of life (QoL). However, an optimal result includes maintaining and improving the QoL. The aim of our study was to evaluate the long-term outcome and the QoL in patients with aneurysms in the ascending aorta; (2) Methods: Between 2014 and 2020, 121 consecutive patients who underwent replacement of the ascending aorta were included in this study. Acute aortic pathologies were excluded. A standard short form (SF)-36 questionnaire was sent to the 112 survivors. According to the surgical procedure, patients were divided into two groups (A: supracoronary replacement of the aorta, n = 35 and B: Wheat-, David- or Bentall-procedures, n = 86). The QoL was compared within these groups and to the normal population, including myocardial infarction (MI), coronary artery disease (CAD) and cancer (CAN) patients; (3) Results: 83 patients were males (68.6%) with a mean age of 62.0 ± 12.5 years. Early postoperative outcomes showed comparable results between groups A and B, with a higher re-thoracotomy rate in B (A: 0.0% vs. B: 22.1%, p = 0.002). The 30-day mortality was zero. Overall, mortality during the follow-up was 7.4%. The SF-36 showed a significant decay in both the Physical (PCS) and Mental Component Summary (MCS) in comparison to the normal population (PCS: 41.1 vs. 48.4, p < 0.001; MCS: 42.1 vs. 50.9, p < 0.001) but without significant difference between both groups. Compared to the MI and CAD patients, significantly higher PCS but lower MCS scores were detected (p < 0.05); (4) Conclusions: Replacement of the ascending aorta shows low risk regarding the operative and postoperative outcomes with satisfying long-term results in the QoL. The extent of the surgical procedure does not influence the postoperative QoL. |
format | Online Article Text |
id | pubmed-10342701 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103427012023-07-14 The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta † Hamiko, Marwan Jahnel, Katja Rogaczewski, Julia Schafigh, Myriam Silaschi, Miriam Spaeth, Andre Velten, Markus Roell, Wilhelm Ahmad, Ali El-Sayed Bakhtiary, Farhad J Clin Med Article (1) Background: Despite optimal surgical therapy, replacement of the ascending aorta leads to a significant reduction in the quality of life (QoL). However, an optimal result includes maintaining and improving the QoL. The aim of our study was to evaluate the long-term outcome and the QoL in patients with aneurysms in the ascending aorta; (2) Methods: Between 2014 and 2020, 121 consecutive patients who underwent replacement of the ascending aorta were included in this study. Acute aortic pathologies were excluded. A standard short form (SF)-36 questionnaire was sent to the 112 survivors. According to the surgical procedure, patients were divided into two groups (A: supracoronary replacement of the aorta, n = 35 and B: Wheat-, David- or Bentall-procedures, n = 86). The QoL was compared within these groups and to the normal population, including myocardial infarction (MI), coronary artery disease (CAD) and cancer (CAN) patients; (3) Results: 83 patients were males (68.6%) with a mean age of 62.0 ± 12.5 years. Early postoperative outcomes showed comparable results between groups A and B, with a higher re-thoracotomy rate in B (A: 0.0% vs. B: 22.1%, p = 0.002). The 30-day mortality was zero. Overall, mortality during the follow-up was 7.4%. The SF-36 showed a significant decay in both the Physical (PCS) and Mental Component Summary (MCS) in comparison to the normal population (PCS: 41.1 vs. 48.4, p < 0.001; MCS: 42.1 vs. 50.9, p < 0.001) but without significant difference between both groups. Compared to the MI and CAD patients, significantly higher PCS but lower MCS scores were detected (p < 0.05); (4) Conclusions: Replacement of the ascending aorta shows low risk regarding the operative and postoperative outcomes with satisfying long-term results in the QoL. The extent of the surgical procedure does not influence the postoperative QoL. MDPI 2023-07-05 /pmc/articles/PMC10342701/ /pubmed/37445533 http://dx.doi.org/10.3390/jcm12134498 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Hamiko, Marwan Jahnel, Katja Rogaczewski, Julia Schafigh, Myriam Silaschi, Miriam Spaeth, Andre Velten, Markus Roell, Wilhelm Ahmad, Ali El-Sayed Bakhtiary, Farhad The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta † |
title | The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta † |
title_full | The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta † |
title_fullStr | The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta † |
title_full_unstemmed | The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta † |
title_short | The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta † |
title_sort | long-term outcome and quality of life after replacement of the ascending aorta † |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342701/ https://www.ncbi.nlm.nih.gov/pubmed/37445533 http://dx.doi.org/10.3390/jcm12134498 |
work_keys_str_mv | AT hamikomarwan thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT jahnelkatja thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT rogaczewskijulia thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT schafighmyriam thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT silaschimiriam thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT spaethandre thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT veltenmarkus thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT roellwilhelm thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT ahmadalielsayed thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT bakhtiaryfarhad thelongtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT hamikomarwan longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT jahnelkatja longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT rogaczewskijulia longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT schafighmyriam longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT silaschimiriam longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT spaethandre longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT veltenmarkus longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT roellwilhelm longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT ahmadalielsayed longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta AT bakhtiaryfarhad longtermoutcomeandqualityoflifeafterreplacementoftheascendingaorta |