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rAAV TGF-β and FGF-2 Overexpression via pNaSS-Grafted PCL Films Stimulates the Reparative Activities of Human ACL Fibroblasts

Lesions in the human anterior cruciate ligament (ACL) are frequent, unsolved clinical issues due to the limited self-healing ability of the ACL and lack of treatments supporting full, durable ACL repair. Gene therapy guided through the use of biomaterials may steadily activate the processes of repai...

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Detalles Bibliográficos
Autores principales: Amini, Mahnaz, Venkatesan, Jagadeesh K., Nguyen, Tuan N., Liu, Wei, Leroux, Amélie, Madry, Henning, Migonney, Véronique, Cucchiarini, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342749/
https://www.ncbi.nlm.nih.gov/pubmed/37446318
http://dx.doi.org/10.3390/ijms241311140