The Role of Low-Dose Oral Methotrexate in Increasing Anti-TNF Drug Levels and Reducing Immunogenicity in IBD

Concomitant immunomodulation is utilised in combination with anti-TNF therapy for IBD primarily to increase drug levels and prevent anti-drug antibody formation. Whilst thiopurines have traditionally been the immunomodulator of choice in IBD populations, there are concerns regarding the long-term sa...

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Detalles Bibliográficos
Autores principales: Demase, Kathryn, Monitto, Cassandra K., Little, Robert D., Sparrow, Miles P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342824/
https://www.ncbi.nlm.nih.gov/pubmed/37445417
http://dx.doi.org/10.3390/jcm12134382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342824/
https://www.ncbi.nlm.nih.gov/pubmed/37445417
http://dx.doi.org/10.3390/jcm12134382

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