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The Treatment of Severe Periodontitis Using a Local Antiseptic Desiccant and Subgingival Mechanical Instrumentation: A Pilot Study

This randomized, split-mouth, controlled clinical study assessed the additional clinical benefits of a local desiccant antimicrobial agent (HY) combined with subgingival mechanical instrumentation (SRP) vs. SRP alone in treating severe periodontitis. Patients with stages III and IV periodontitis rec...

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Autores principales: Soancă, Andrada, Leucuța, Daniel Corneliu, Roman, Alexandra, Ciurea, Andreea, Negucioiu, Marius, Pascu, Laurențiu Cătălin, Picoș, Andrei, Delean, Ada Gabriela, Micu, Iulia Cristina, Popa Wagner, Aurel, Rusu, Darian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342826/
https://www.ncbi.nlm.nih.gov/pubmed/37445321
http://dx.doi.org/10.3390/jcm12134286
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author Soancă, Andrada
Leucuța, Daniel Corneliu
Roman, Alexandra
Ciurea, Andreea
Negucioiu, Marius
Pascu, Laurențiu Cătălin
Picoș, Andrei
Delean, Ada Gabriela
Micu, Iulia Cristina
Popa Wagner, Aurel
Rusu, Darian
author_facet Soancă, Andrada
Leucuța, Daniel Corneliu
Roman, Alexandra
Ciurea, Andreea
Negucioiu, Marius
Pascu, Laurențiu Cătălin
Picoș, Andrei
Delean, Ada Gabriela
Micu, Iulia Cristina
Popa Wagner, Aurel
Rusu, Darian
author_sort Soancă, Andrada
collection PubMed
description This randomized, split-mouth, controlled clinical study assessed the additional clinical benefits of a local desiccant antimicrobial agent (HY) combined with subgingival mechanical instrumentation (SRP) vs. SRP alone in treating severe periodontitis. Patients with stages III and IV periodontitis received full-mouth periodontal examinations at baseline and after a three-month follow-up. Two randomly selected hemiarches in each periodontitis patient were treated with SRP plus HY and were included in the test group, while the other two hemiarches received only SRP and were included in the control group. In thirty patients, the analyses of the evolution of the periodontal parameters over time showed statistically significant mean differences for the probing depths and clinical attachment level values resulting from all the examined sites, as well as from the interproximal sites (p < 0.001) in both the test and control groups. The intergroup comparisons of the same four parameters showed no significant differences (p = 0.322, p = 0.36, p = 0.516, and p = 0.509, respectively). Based on these study results, no additional benefits were obtained after HY subgingival applications.
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spelling pubmed-103428262023-07-14 The Treatment of Severe Periodontitis Using a Local Antiseptic Desiccant and Subgingival Mechanical Instrumentation: A Pilot Study Soancă, Andrada Leucuța, Daniel Corneliu Roman, Alexandra Ciurea, Andreea Negucioiu, Marius Pascu, Laurențiu Cătălin Picoș, Andrei Delean, Ada Gabriela Micu, Iulia Cristina Popa Wagner, Aurel Rusu, Darian J Clin Med Article This randomized, split-mouth, controlled clinical study assessed the additional clinical benefits of a local desiccant antimicrobial agent (HY) combined with subgingival mechanical instrumentation (SRP) vs. SRP alone in treating severe periodontitis. Patients with stages III and IV periodontitis received full-mouth periodontal examinations at baseline and after a three-month follow-up. Two randomly selected hemiarches in each periodontitis patient were treated with SRP plus HY and were included in the test group, while the other two hemiarches received only SRP and were included in the control group. In thirty patients, the analyses of the evolution of the periodontal parameters over time showed statistically significant mean differences for the probing depths and clinical attachment level values resulting from all the examined sites, as well as from the interproximal sites (p < 0.001) in both the test and control groups. The intergroup comparisons of the same four parameters showed no significant differences (p = 0.322, p = 0.36, p = 0.516, and p = 0.509, respectively). Based on these study results, no additional benefits were obtained after HY subgingival applications. MDPI 2023-06-26 /pmc/articles/PMC10342826/ /pubmed/37445321 http://dx.doi.org/10.3390/jcm12134286 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Soancă, Andrada
Leucuța, Daniel Corneliu
Roman, Alexandra
Ciurea, Andreea
Negucioiu, Marius
Pascu, Laurențiu Cătălin
Picoș, Andrei
Delean, Ada Gabriela
Micu, Iulia Cristina
Popa Wagner, Aurel
Rusu, Darian
The Treatment of Severe Periodontitis Using a Local Antiseptic Desiccant and Subgingival Mechanical Instrumentation: A Pilot Study
title The Treatment of Severe Periodontitis Using a Local Antiseptic Desiccant and Subgingival Mechanical Instrumentation: A Pilot Study
title_full The Treatment of Severe Periodontitis Using a Local Antiseptic Desiccant and Subgingival Mechanical Instrumentation: A Pilot Study
title_fullStr The Treatment of Severe Periodontitis Using a Local Antiseptic Desiccant and Subgingival Mechanical Instrumentation: A Pilot Study
title_full_unstemmed The Treatment of Severe Periodontitis Using a Local Antiseptic Desiccant and Subgingival Mechanical Instrumentation: A Pilot Study
title_short The Treatment of Severe Periodontitis Using a Local Antiseptic Desiccant and Subgingival Mechanical Instrumentation: A Pilot Study
title_sort treatment of severe periodontitis using a local antiseptic desiccant and subgingival mechanical instrumentation: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342826/
https://www.ncbi.nlm.nih.gov/pubmed/37445321
http://dx.doi.org/10.3390/jcm12134286
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