Cargando…

Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity

Obesity is becoming one of the major global health concerns. This chronic disease affects around 650 million people worldwide and is an underlying cause of a number of significant comorbidities. According to the World Health Organization (WHO) report on obesity from 2022, this disorder became the fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Szmygin, Hanna, Szmygin, Maciej, Cheda, Mateusz, Kłobuszewski, Bartosz, Drelich-Zbroja, Anna, Matyjaszek-Matuszek, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342891/
https://www.ncbi.nlm.nih.gov/pubmed/37445414
http://dx.doi.org/10.3390/jcm12134379
_version_ 1785072607668731904
author Szmygin, Hanna
Szmygin, Maciej
Cheda, Mateusz
Kłobuszewski, Bartosz
Drelich-Zbroja, Anna
Matyjaszek-Matuszek, Beata
author_facet Szmygin, Hanna
Szmygin, Maciej
Cheda, Mateusz
Kłobuszewski, Bartosz
Drelich-Zbroja, Anna
Matyjaszek-Matuszek, Beata
author_sort Szmygin, Hanna
collection PubMed
description Obesity is becoming one of the major global health concerns. This chronic disease affects around 650 million people worldwide and is an underlying cause of a number of significant comorbidities. According to the World Health Organization (WHO) report on obesity from 2022, this disorder became the fourth leading cause of deaths in Europe. Thus, understanding the mechanisms underlying obesity is of essential importance to successfully prevent and treat this disease. The aim of this study was to review the current insights into the potential role of fMRI in discovering the mechanisms underlying obesity on the basis of recent scientific literature published up to December 2022 and searches of the PubMed, Google Scholar and Web of Science databases. The literature assessed indicated that a growing body of evidence suggests that obesity leads to changes in both structure and connectivity within the central nervous system. Emerging data from recent functional magnetic resonance imaging (fMRI) studies prove that obese individuals present an increased motivational drive to eat as well as impaired processing in reward- and control-related brain regions. Apart from this, it is clear that fMRI might be a useful tool in detection of obesity-induced changes within the central nervous system.
format Online
Article
Text
id pubmed-10342891
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-103428912023-07-14 Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity Szmygin, Hanna Szmygin, Maciej Cheda, Mateusz Kłobuszewski, Bartosz Drelich-Zbroja, Anna Matyjaszek-Matuszek, Beata J Clin Med Review Obesity is becoming one of the major global health concerns. This chronic disease affects around 650 million people worldwide and is an underlying cause of a number of significant comorbidities. According to the World Health Organization (WHO) report on obesity from 2022, this disorder became the fourth leading cause of deaths in Europe. Thus, understanding the mechanisms underlying obesity is of essential importance to successfully prevent and treat this disease. The aim of this study was to review the current insights into the potential role of fMRI in discovering the mechanisms underlying obesity on the basis of recent scientific literature published up to December 2022 and searches of the PubMed, Google Scholar and Web of Science databases. The literature assessed indicated that a growing body of evidence suggests that obesity leads to changes in both structure and connectivity within the central nervous system. Emerging data from recent functional magnetic resonance imaging (fMRI) studies prove that obese individuals present an increased motivational drive to eat as well as impaired processing in reward- and control-related brain regions. Apart from this, it is clear that fMRI might be a useful tool in detection of obesity-induced changes within the central nervous system. MDPI 2023-06-29 /pmc/articles/PMC10342891/ /pubmed/37445414 http://dx.doi.org/10.3390/jcm12134379 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Szmygin, Hanna
Szmygin, Maciej
Cheda, Mateusz
Kłobuszewski, Bartosz
Drelich-Zbroja, Anna
Matyjaszek-Matuszek, Beata
Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity
title Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity
title_full Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity
title_fullStr Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity
title_full_unstemmed Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity
title_short Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity
title_sort current insights into the potential role of fmri in discovering the mechanisms underlying obesity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342891/
https://www.ncbi.nlm.nih.gov/pubmed/37445414
http://dx.doi.org/10.3390/jcm12134379
work_keys_str_mv AT szmyginhanna currentinsightsintothepotentialroleoffmriindiscoveringthemechanismsunderlyingobesity
AT szmyginmaciej currentinsightsintothepotentialroleoffmriindiscoveringthemechanismsunderlyingobesity
AT chedamateusz currentinsightsintothepotentialroleoffmriindiscoveringthemechanismsunderlyingobesity
AT kłobuszewskibartosz currentinsightsintothepotentialroleoffmriindiscoveringthemechanismsunderlyingobesity
AT drelichzbrojaanna currentinsightsintothepotentialroleoffmriindiscoveringthemechanismsunderlyingobesity
AT matyjaszekmatuszekbeata currentinsightsintothepotentialroleoffmriindiscoveringthemechanismsunderlyingobesity