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Aortic Dilatation on the Edge of Dissection—Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR)

(1) Background: There is a need for a novel surrogate marker to ease decision making when facing ascending aortic dilatation. In this article, we study the ratio between ascending and descending aorta diameters as a potential one. (2) Methods: Retrospective observational cohort study, including all...

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Autores principales: Lopez Perez, Nerea, Reymond, Philippe, Cikirikcioglu, Mustafa, van Steenberghe, Mathieu, Sologashvili, Tornike, Murith, Nicolas, Perneger, Thomas, Huber, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342912/
https://www.ncbi.nlm.nih.gov/pubmed/37445435
http://dx.doi.org/10.3390/jcm12134400
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author Lopez Perez, Nerea
Reymond, Philippe
Cikirikcioglu, Mustafa
van Steenberghe, Mathieu
Sologashvili, Tornike
Murith, Nicolas
Perneger, Thomas
Huber, Christoph
author_facet Lopez Perez, Nerea
Reymond, Philippe
Cikirikcioglu, Mustafa
van Steenberghe, Mathieu
Sologashvili, Tornike
Murith, Nicolas
Perneger, Thomas
Huber, Christoph
author_sort Lopez Perez, Nerea
collection PubMed
description (1) Background: There is a need for a novel surrogate marker to ease decision making when facing ascending aortic dilatation. In this article, we study the ratio between ascending and descending aorta diameters as a potential one. (2) Methods: Retrospective observational cohort study, including all the patients who underwent surgery for acute type A aorta dissection (aTAAD) between January 2014 and September 2020 at our center. A total of 50 patients were included. Clinical and demographic data were collected. The anatomical measurements were made including orthogonal maximal diameters of the ascending and descending aorta, post-dissection whole circumference length (post-wCL), post-dissection true lumen circumference length (post-tCL), and surface and sphericity indices of the ascending and descending aorta. Pre-dissection ascending aorta diameter (pre-AAD) and pre-dissection descending aorta diameter (pre-DAD) were calculated as well as the ratio between them and compared with reference values. (3) Results: Of the pre-AAD patients, 96% had smaller than the recommended 55 mm. The ratio between the descending and ascending aorta pre-dissection diameters was significantly smaller compared to the reference value (0.657 ± 0.125 versus 0.745 ± 0.016 with a mean difference of −0.088 and a p < 0.001). (4) Conclusions: The 55 mm threshold for aorta maximal diameter is an insufficient criterion when assessing the risk of dissection. The ratio between DAD and AAD is a parameter worthy of analysis as a tool to stratify the risk of dissection.
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spelling pubmed-103429122023-07-14 Aortic Dilatation on the Edge of Dissection—Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR) Lopez Perez, Nerea Reymond, Philippe Cikirikcioglu, Mustafa van Steenberghe, Mathieu Sologashvili, Tornike Murith, Nicolas Perneger, Thomas Huber, Christoph J Clin Med Article (1) Background: There is a need for a novel surrogate marker to ease decision making when facing ascending aortic dilatation. In this article, we study the ratio between ascending and descending aorta diameters as a potential one. (2) Methods: Retrospective observational cohort study, including all the patients who underwent surgery for acute type A aorta dissection (aTAAD) between January 2014 and September 2020 at our center. A total of 50 patients were included. Clinical and demographic data were collected. The anatomical measurements were made including orthogonal maximal diameters of the ascending and descending aorta, post-dissection whole circumference length (post-wCL), post-dissection true lumen circumference length (post-tCL), and surface and sphericity indices of the ascending and descending aorta. Pre-dissection ascending aorta diameter (pre-AAD) and pre-dissection descending aorta diameter (pre-DAD) were calculated as well as the ratio between them and compared with reference values. (3) Results: Of the pre-AAD patients, 96% had smaller than the recommended 55 mm. The ratio between the descending and ascending aorta pre-dissection diameters was significantly smaller compared to the reference value (0.657 ± 0.125 versus 0.745 ± 0.016 with a mean difference of −0.088 and a p < 0.001). (4) Conclusions: The 55 mm threshold for aorta maximal diameter is an insufficient criterion when assessing the risk of dissection. The ratio between DAD and AAD is a parameter worthy of analysis as a tool to stratify the risk of dissection. MDPI 2023-06-29 /pmc/articles/PMC10342912/ /pubmed/37445435 http://dx.doi.org/10.3390/jcm12134400 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lopez Perez, Nerea
Reymond, Philippe
Cikirikcioglu, Mustafa
van Steenberghe, Mathieu
Sologashvili, Tornike
Murith, Nicolas
Perneger, Thomas
Huber, Christoph
Aortic Dilatation on the Edge of Dissection—Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR)
title Aortic Dilatation on the Edge of Dissection—Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR)
title_full Aortic Dilatation on the Edge of Dissection—Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR)
title_fullStr Aortic Dilatation on the Edge of Dissection—Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR)
title_full_unstemmed Aortic Dilatation on the Edge of Dissection—Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR)
title_short Aortic Dilatation on the Edge of Dissection—Do We Operate Too Late? The Ratio between Ascending and Descending Aorta DiameteR (RADAR)
title_sort aortic dilatation on the edge of dissection—do we operate too late? the ratio between ascending and descending aorta diameter (radar)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342912/
https://www.ncbi.nlm.nih.gov/pubmed/37445435
http://dx.doi.org/10.3390/jcm12134400
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