S-Ethyl-Isothiocitrullin-Based Dipeptides and 1,2,4-Oxadiazole Pseudo-Dipeptides: Solid Phase Synthesis and Evaluation as NO Synthase Inhibitors

We previously reported dipeptidomimetic compounds as inhibitors of neuronal and/or inducible NO synthases (n/iNOS) with significant selectivity against endothelial NOS (eNOS). They were composed of an S-ethylisothiocitrullin-like moiety linked to an extension through a peptide bond or a 1,2,4-oxadia...

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Detalles Bibliográficos
Autores principales: Mauchauffée, Elodie, Leroy, Jérémy, Chamcham, Jihanne, Ejjoummany, Abdelaziz, Maurel, Manon, Nauton, Lionel, Ramassamy, Booma, Mezghenna, Karima, Boucher, Jean-Luc, Lajoix, Anne-Dominique, Hernandez, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343299/
https://www.ncbi.nlm.nih.gov/pubmed/37446746
http://dx.doi.org/10.3390/molecules28135085

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