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Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer
Diet may modulate the risk of head and neck cancer (HNC) through antioxidant and anti-inflammatory effects. To date, there is limited evidence regarding the effects of the Mediterranean diet on HNC risk. The purpose of the study was to assess the association between Mediterranean diet adherence, typ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343316/ https://www.ncbi.nlm.nih.gov/pubmed/37447173 http://dx.doi.org/10.3390/nu15132846 |
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author | Saka-Herrán, Constanza Pereira-Riveros, Tanya Jané-Salas, Enric López-López, José |
author_facet | Saka-Herrán, Constanza Pereira-Riveros, Tanya Jané-Salas, Enric López-López, José |
author_sort | Saka-Herrán, Constanza |
collection | PubMed |
description | Diet may modulate the risk of head and neck cancer (HNC) through antioxidant and anti-inflammatory effects. To date, there is limited evidence regarding the effects of the Mediterranean diet on HNC risk. The purpose of the study was to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. A case–control study was conducted at the Dentistry Hospital, University of Barcelona, including 101 cases of HNC and 101 controls matched by age and sex. Dietary habits were assessed using a 14-question Mediterranean diet score that classified the type of diet into healthy diet (10–14 points), regular diet (5–9 points), and unhealthy diet (≤4 points). Multivariate logistic regression models were used to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. Higher adherence to the Mediterranean diet was significantly associated with a lower risk of HNC (OR = 0.88, 95% CI: 0.79–0.98). A healthy diet (OR = 0.29, 95% CI: 0.10–0.84) and vitamin C intake (OR = 0.25, 95% CI: 0.10–0.62) were strongly associated with lower odds of HNC. Moderate egg intake was the only type of food significantly associated with a lower risk of HNC. Dietary patterns that emphasize a high intake of antioxidant and anti-inflammatory bioactive components may have a protective effect on the risk of HNC. |
format | Online Article Text |
id | pubmed-10343316 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103433162023-07-14 Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer Saka-Herrán, Constanza Pereira-Riveros, Tanya Jané-Salas, Enric López-López, José Nutrients Article Diet may modulate the risk of head and neck cancer (HNC) through antioxidant and anti-inflammatory effects. To date, there is limited evidence regarding the effects of the Mediterranean diet on HNC risk. The purpose of the study was to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. A case–control study was conducted at the Dentistry Hospital, University of Barcelona, including 101 cases of HNC and 101 controls matched by age and sex. Dietary habits were assessed using a 14-question Mediterranean diet score that classified the type of diet into healthy diet (10–14 points), regular diet (5–9 points), and unhealthy diet (≤4 points). Multivariate logistic regression models were used to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. Higher adherence to the Mediterranean diet was significantly associated with a lower risk of HNC (OR = 0.88, 95% CI: 0.79–0.98). A healthy diet (OR = 0.29, 95% CI: 0.10–0.84) and vitamin C intake (OR = 0.25, 95% CI: 0.10–0.62) were strongly associated with lower odds of HNC. Moderate egg intake was the only type of food significantly associated with a lower risk of HNC. Dietary patterns that emphasize a high intake of antioxidant and anti-inflammatory bioactive components may have a protective effect on the risk of HNC. MDPI 2023-06-23 /pmc/articles/PMC10343316/ /pubmed/37447173 http://dx.doi.org/10.3390/nu15132846 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Saka-Herrán, Constanza Pereira-Riveros, Tanya Jané-Salas, Enric López-López, José Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer |
title | Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer |
title_full | Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer |
title_fullStr | Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer |
title_full_unstemmed | Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer |
title_short | Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer |
title_sort | association between the mediterranean diet and vitamin c and the risk of head and neck cancer |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343316/ https://www.ncbi.nlm.nih.gov/pubmed/37447173 http://dx.doi.org/10.3390/nu15132846 |
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