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Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer

Diet may modulate the risk of head and neck cancer (HNC) through antioxidant and anti-inflammatory effects. To date, there is limited evidence regarding the effects of the Mediterranean diet on HNC risk. The purpose of the study was to assess the association between Mediterranean diet adherence, typ...

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Autores principales: Saka-Herrán, Constanza, Pereira-Riveros, Tanya, Jané-Salas, Enric, López-López, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343316/
https://www.ncbi.nlm.nih.gov/pubmed/37447173
http://dx.doi.org/10.3390/nu15132846
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author Saka-Herrán, Constanza
Pereira-Riveros, Tanya
Jané-Salas, Enric
López-López, José
author_facet Saka-Herrán, Constanza
Pereira-Riveros, Tanya
Jané-Salas, Enric
López-López, José
author_sort Saka-Herrán, Constanza
collection PubMed
description Diet may modulate the risk of head and neck cancer (HNC) through antioxidant and anti-inflammatory effects. To date, there is limited evidence regarding the effects of the Mediterranean diet on HNC risk. The purpose of the study was to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. A case–control study was conducted at the Dentistry Hospital, University of Barcelona, including 101 cases of HNC and 101 controls matched by age and sex. Dietary habits were assessed using a 14-question Mediterranean diet score that classified the type of diet into healthy diet (10–14 points), regular diet (5–9 points), and unhealthy diet (≤4 points). Multivariate logistic regression models were used to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. Higher adherence to the Mediterranean diet was significantly associated with a lower risk of HNC (OR = 0.88, 95% CI: 0.79–0.98). A healthy diet (OR = 0.29, 95% CI: 0.10–0.84) and vitamin C intake (OR = 0.25, 95% CI: 0.10–0.62) were strongly associated with lower odds of HNC. Moderate egg intake was the only type of food significantly associated with a lower risk of HNC. Dietary patterns that emphasize a high intake of antioxidant and anti-inflammatory bioactive components may have a protective effect on the risk of HNC.
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spelling pubmed-103433162023-07-14 Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer Saka-Herrán, Constanza Pereira-Riveros, Tanya Jané-Salas, Enric López-López, José Nutrients Article Diet may modulate the risk of head and neck cancer (HNC) through antioxidant and anti-inflammatory effects. To date, there is limited evidence regarding the effects of the Mediterranean diet on HNC risk. The purpose of the study was to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. A case–control study was conducted at the Dentistry Hospital, University of Barcelona, including 101 cases of HNC and 101 controls matched by age and sex. Dietary habits were assessed using a 14-question Mediterranean diet score that classified the type of diet into healthy diet (10–14 points), regular diet (5–9 points), and unhealthy diet (≤4 points). Multivariate logistic regression models were used to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. Higher adherence to the Mediterranean diet was significantly associated with a lower risk of HNC (OR = 0.88, 95% CI: 0.79–0.98). A healthy diet (OR = 0.29, 95% CI: 0.10–0.84) and vitamin C intake (OR = 0.25, 95% CI: 0.10–0.62) were strongly associated with lower odds of HNC. Moderate egg intake was the only type of food significantly associated with a lower risk of HNC. Dietary patterns that emphasize a high intake of antioxidant and anti-inflammatory bioactive components may have a protective effect on the risk of HNC. MDPI 2023-06-23 /pmc/articles/PMC10343316/ /pubmed/37447173 http://dx.doi.org/10.3390/nu15132846 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Saka-Herrán, Constanza
Pereira-Riveros, Tanya
Jané-Salas, Enric
López-López, José
Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer
title Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer
title_full Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer
title_fullStr Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer
title_full_unstemmed Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer
title_short Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer
title_sort association between the mediterranean diet and vitamin c and the risk of head and neck cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343316/
https://www.ncbi.nlm.nih.gov/pubmed/37447173
http://dx.doi.org/10.3390/nu15132846
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