Cargando…

Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice

The effects of insoluble dietary fiber from fresh corn bracts modified by dynamic high-pressure micro-fluidization (DHPM) on the pathological characteristics of obesity, intestinal microflora distribution and production of short-chain fatty acids in high-fat-diet C57BL/6 mice were evaluated. The res...

Descripción completa

Detalles Bibliográficos
Autores principales: Geng, Ningning, Li, Ying, Zhang, Yan, Wang, Hongjuan, Song, Jiangfeng, Yu, Lijun, Wu, Caie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343396/
https://www.ncbi.nlm.nih.gov/pubmed/37446612
http://dx.doi.org/10.3390/molecules28134949
_version_ 1785072727184375808
author Geng, Ningning
Li, Ying
Zhang, Yan
Wang, Hongjuan
Song, Jiangfeng
Yu, Lijun
Wu, Caie
author_facet Geng, Ningning
Li, Ying
Zhang, Yan
Wang, Hongjuan
Song, Jiangfeng
Yu, Lijun
Wu, Caie
author_sort Geng, Ningning
collection PubMed
description The effects of insoluble dietary fiber from fresh corn bracts modified by dynamic high-pressure micro-fluidization (DHPM) on the pathological characteristics of obesity, intestinal microflora distribution and production of short-chain fatty acids in high-fat-diet C57BL/6 mice were evaluated. The results show that the DHPM-modified dietary fiber from fresh corn bracts significantly reduces weight gain, insulin resistance and oxidative damage caused by a high-fat diet, and promotes the production of SCFAs, especially acetic acid, propionic acid and butyric acid. These modified dietary fibers also change the proportion of different types of bacteria in the intestinal microflora of mice, reduce the ratio of Firmicutes and Bacteroidota and promote the proliferation of Bifidobacteriales. Therefore, the DHPM-modified dietary fiber from fresh corn bracts can be used as a good intestinal microbiota regulator to promote intestinal health, thereby achieving the role of preventing and treating obesity.
format Online
Article
Text
id pubmed-10343396
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-103433962023-07-14 Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice Geng, Ningning Li, Ying Zhang, Yan Wang, Hongjuan Song, Jiangfeng Yu, Lijun Wu, Caie Molecules Article The effects of insoluble dietary fiber from fresh corn bracts modified by dynamic high-pressure micro-fluidization (DHPM) on the pathological characteristics of obesity, intestinal microflora distribution and production of short-chain fatty acids in high-fat-diet C57BL/6 mice were evaluated. The results show that the DHPM-modified dietary fiber from fresh corn bracts significantly reduces weight gain, insulin resistance and oxidative damage caused by a high-fat diet, and promotes the production of SCFAs, especially acetic acid, propionic acid and butyric acid. These modified dietary fibers also change the proportion of different types of bacteria in the intestinal microflora of mice, reduce the ratio of Firmicutes and Bacteroidota and promote the proliferation of Bifidobacteriales. Therefore, the DHPM-modified dietary fiber from fresh corn bracts can be used as a good intestinal microbiota regulator to promote intestinal health, thereby achieving the role of preventing and treating obesity. MDPI 2023-06-23 /pmc/articles/PMC10343396/ /pubmed/37446612 http://dx.doi.org/10.3390/molecules28134949 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Geng, Ningning
Li, Ying
Zhang, Yan
Wang, Hongjuan
Song, Jiangfeng
Yu, Lijun
Wu, Caie
Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice
title Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice
title_full Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice
title_fullStr Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice
title_full_unstemmed Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice
title_short Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice
title_sort effects of modified dietary fiber from fresh corn bracts on obesity and intestinal microbiota in high-fat-diet mice
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343396/
https://www.ncbi.nlm.nih.gov/pubmed/37446612
http://dx.doi.org/10.3390/molecules28134949
work_keys_str_mv AT gengningning effectsofmodifieddietaryfiberfromfreshcornbractsonobesityandintestinalmicrobiotainhighfatdietmice
AT liying effectsofmodifieddietaryfiberfromfreshcornbractsonobesityandintestinalmicrobiotainhighfatdietmice
AT zhangyan effectsofmodifieddietaryfiberfromfreshcornbractsonobesityandintestinalmicrobiotainhighfatdietmice
AT wanghongjuan effectsofmodifieddietaryfiberfromfreshcornbractsonobesityandintestinalmicrobiotainhighfatdietmice
AT songjiangfeng effectsofmodifieddietaryfiberfromfreshcornbractsonobesityandintestinalmicrobiotainhighfatdietmice
AT yulijun effectsofmodifieddietaryfiberfromfreshcornbractsonobesityandintestinalmicrobiotainhighfatdietmice
AT wucaie effectsofmodifieddietaryfiberfromfreshcornbractsonobesityandintestinalmicrobiotainhighfatdietmice