Metabolomics revealed mechanism for the synergistic effect of sulbactam, polymyxin-B and amikacin combination against Acinetobacter baumannii

INTRODUCTION: The emergence of multidrug-resistant (MDR) Acinetobacter baumannii prompts clinicians to consider treating these infections with polymyxin combination. METHODS: Metabolomic analysis was applied to investigate the synergistic effects of polymyxin-B, amikacin and sulbactam combination th...

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Detalles Bibliográficos
Autores principales: Zhu, Shixing, Yue, Jiali, Wang, Xintong, Zhang, Jiayuan, Yu, Mingming, Zhan, Yuanchao, Zhu, Yuanqi, Sy, Sherwin K. B., Lv, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343439/
https://www.ncbi.nlm.nih.gov/pubmed/37455727
http://dx.doi.org/10.3389/fmicb.2023.1217270

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