The Strength of hERG Inhibition by Erythromycin at Different Temperatures Might Be Due to Its Interacting Features with the Channels

Erythromycin is one of the few compounds that remarkably increase ether-a-go-go-related gene (hERG) inhibition from room temperature (RT) to physiological temperature (PT). Understanding how erythromycin inhibits the hERG could help us to decide which compounds are needed for further studies. The wh...

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Detalles Bibliográficos
Autores principales: Cheng, Dongrong, Wei, Xiaofeng, Zhang, Yanting, Zhang, Qian, Xu, Jianwei, Yang, Jiaxin, Yu, Junjie, Stalin, Antony, Liu, Huan, Wang, Jintao, Zhong, Dian, Pan, Lanying, Zhao, Wei, Chen, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343501/
https://www.ncbi.nlm.nih.gov/pubmed/37446837
http://dx.doi.org/10.3390/molecules28135176

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