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In Silico Studies of Novel Vemurafenib Derivatives as BRAF Kinase Inhibitors
BRAF inhibitors have improved the treatment of advanced or metastatic melanoma in patients that harbor a BRAF(T1799A) mutation. Because of new insights into the role of aberrant glycosylation in drug resistance, we designed and studied three novel vemurafenib derivatives possessing pentose-associate...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343629/ https://www.ncbi.nlm.nih.gov/pubmed/37446932 http://dx.doi.org/10.3390/molecules28135273 |